Tag: XMRV

XMRV Chronic Fatigue Syndrome Update

Sometimes science works the way it’s supposed to. Scientists make hypotheses, test them by gathering preliminary evidence, and then argue about the inevitable conflicting results. Eventually better and better evidence is gathered until a consensus is achieved. Actually, I think that is how science usually works, it’s just that most questions in science are narrow and technical and don’t command media or...

/ September 26, 2012
Test tubes laboratory

Followup: More Evidence against the XMRV Virus as a Cause of Chronic Fatigue Syndrome

A mouse leukemia retrovirus, xenotropic murine leukemia virus-related virus (XMRV retrovirus), has been under consideration as a possible cause of chronic fatigue syndrome (CFS, and also prostate cancer). In a study published in Science in October 2009, Lombardi et al. found XMRV in 67% of CFS patients and 3.7% of controls. Several subsequent studies in the UK, the Netherlands, and the US...

/ January 4, 2011
waves in a pond

Chronic Fatigue Syndrome: Lots of Speculation

Humans love to find patterns in the world. Sometimes patterns exist, sometimes they are imaginary. Sometimes you can see a pattern that may be interesting and ignore its significance. As a resident I used to say that anyone who smokes three packs of cigarettes a day has to be schizophrenic, it was meant more as a joke, when, in fact, it was...

/ September 10, 2010
Mouse-eating

Chronic Fatigue Syndrome and Retroviruses: Jumping the Gun

When I first heard that a retrovirus had been identified as a possible cause of chronic fatigue syndrome, I withheld judgment and awaited further developments. When I heard that two subsequent studies had failed to replicate the findings of the first, I assumed that the first had been a false alarm and would be disregarded. Not so.  It’s a classic case of...

/ February 23, 2010
White_lab_mouse eating

CFS: Viral vs somatization

If the association is confirmed, the finding will have near-revolutionary implications for our understanding disease – particularly infectious disease. If there is a confirmed model for such a vague set of symptoms signifying some occult infection limited to immune cells, which produces no repeatable cellular or antibody abnormality, no susceptibility to other infections (such as with HIV) and in which the sites...

/ October 14, 2009