Category: Clinical Trials

A meta-analysis delivered to the offices of JAMA

Spinal Manipulation and the JAMA Meta-Analysis: An Analysis of Fuel.

Association of Spinal Manipulative Therapy With Clinical Benefit and Harm for Acute Low Back Pain: Systematic Review and Meta-analysis. It is even worse than I thought it would be.

/ April 28, 2017
Vice President Mike Pence is a supporter of right-to-try, having signed Indiana's right-to-try bill into law when he was the Governor of Indiana.

The cruel sham that is right-to-try raises its ugly head at the federal level again

Ill-advised right-to-try bills are spreading like kudzu through state legislatures. Now federal legislators want to insert right-to-try language into the bill that funds FDA drug approval. Given the support of powerful Republicans like Vice President Mike Pence for right-to-try, is it too late to stop this juggernaut and protect patients?

/ April 17, 2017
Donald Trump

Medical science policy in the U.S. under Donald Trump eighty days in

A week after Donald Trump was elected, I speculated about how he would affect medical science policy. Now, 80 days into the Trump administration, we have some observations.

/ April 10, 2017
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Corrigendum. The Week in Review for 04/09/2017

The NECSS is coming. Acupuncturists mimic chiropractic. Flu vaccine prevents death. In the UK they care more for cats than people. The problem is my middle burner, not too many burgers. And more.

/ April 9, 2017
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Treating Chronic Fatigue Syndrome with Cognitive Behavioral Therapy and Graded Exercise Therapy: How the PACE Trial Got It Wrong

The PACE trial found that cognitive behavioral therapy and graded exercise therapy were effective treatments for chronic fatigue syndrome and could produce recovery in 22% of patients. It seems they got it wrong.

/ April 4, 2017
A thousand points of pseudo-medicine.

Corrigendum. The Week in Review for 04/02/2017

Death from vaccine-preventable infections. Homeopathy and acupuncture do not work. There is a difference between cost and worth. And more.

/ April 2, 2017
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Vitamin C and Sepsis. All Sound and Fury? Much Ado About Nothing?

Is intravenous vitamin C helpful in sepsis? I hope so, but past experience render me skeptical.

/ March 31, 2017
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Stem Cells for Macular Degeneration: Meticulous Science vs. Unethical Carelessness

Rigorous scientists stabilized a patient’s macular degeneration with a cutting-edge stem cell treatment; less rigorous scientists misapplied stem cell science and left three women blind.

/ March 28, 2017
The four ages of man aging

Update on Testosterone Supplementation

Testosterone supplementation is a legitimate treatment for properly-diagnosed androgen deficiency, but it is being overprescribed by doctors who make exaggerated claims for it. New evidence clarifies its modest benefits and worrisome risks.

/ March 14, 2017
Stanislaw Burzynski, pretending to do science.

The Texas Medical Board lets Stanislaw Burzynski off lightly: A cautionary tale of the failure of regulating medicine

After three years and countless twists and turns, the final decision by the Texas Medical Board on the sanctions to be imposed on Houston cancer quack Dr. Stanislaw Burzynski were announced on Friday. Sadly, they were not enough. The Burzynski saga should serve as a cautionary tale that the regulation of physicians and medicine is too lax, not too strict.

/ March 6, 2017