Category: Clinical Trials

The final push to pass a federal version of the cruel sham of “right-to-try” is under way

Right-to-try laws are a cruel sham that claim to help terminally ill patients by providing them with earlier access to experimental therapeutics, even though they do very little in this regard. Promoted primarily by the libertarian think tank the Goldwater Institute, in reality they are a strategy to weaken the FDA's regulatory power to assure that marketed drugs are safe and effective....

/ January 15, 2018

A Misguided Study to Test the Reliability of Traditional Chinese Medicine Pulse Diagnosis

Pulse diagnosis and tongue diagnosis are widely used in traditional Chinese medicine. They are based on imagination, not on anatomical and physiologic reality.

/ December 26, 2017

I Was Wrong about Protandim

A seriously flawed Protandim study seemed to show that side effects were no more common than with placebo. Actually, they were almost twice as common. The researchers were looking at the wrong numbers and didn't even add correctly.

/ December 5, 2017

CAM use leads to delays in appropriate, effective arthritis therapy

A preference to use CAM before seeking medical advice may be harming patients with inflammatory arthritis.

/ November 16, 2017

Update on ASEA, Protandim, and dōTERRA

Multilevel marketing distributors of dietary supplements and essential oils point to studies that they think constitute evidence that their products work. They don't understand why those studies are inadequate.

/ November 7, 2017

ORBITA: Another clinical trial demonstrating the need for sham controls in surgical trials

Last week, the results of ORBITA were published. This clinical trial tested coronary angioplasty and stenting versus optimal medical management in patients with single-vessel coronary artery disease. It was a resoundingly negative trial, meaning that adding stenting to drug management didn't result in detectable clinical improvement. What was distinctive about this trial is that it used a sham procedure (i.e., placebo) control,...

/ November 6, 2017

Rigvir strikes back, or: A conversation with a Rigvir flack

My skeptical analysis of Rigvir, a "Virotherapy" from Latvia being promoted by alternative medicine clinics as a cancer cure, caught the attention of the International Virotherapy Center (IVC). The result was a long and very telling e-mail exchange between its Assistant of Business Development and myself. I post it because the arguments used in the discussion are very telling about where the...

/ October 2, 2017

Ty Bollinger’s “The Truth About Cancer” and the unethical marketing of the unproven cancer virotherapy Rigvir

Last week, I wrote about Rigvir, a "virotherapy" promoted by the International Virotherapy Center (IVC) in Latvia, which did not like what I had to say. When a representative called me to task for referring to the marketing of Rigvir using patient testimonials as irresponsbile, it prompted me to look at how Ty Bollinger's The Truth About Cancer series promoted Rigvir through...

/ September 25, 2017

Rigvir: Another unproven and dubious cancer therapy to be avoided

Recently, the Hope4Cancer Institute, a quack clinic in Mexico, has added a treatment known as Rigvir to its coffee enemas and other offerings. But what is Rigvir? It turns out that it's an import from Latvia with a mysterious history. Proponents claim that it is an oncolytic virus that targets cancer specifically and leaves normal cells alone. Unfortunately, there is a profound...

/ September 18, 2017

“New vaccine replaces statins?” Not So Fast!

News reports suggest new drugs may replace statins. PSCK9 inhibitors are useful, but only along with statins in high risk patients not controlled on statins alone, or for patients who can't tolerate statins. They're not about to replace statins.

/ September 5, 2017