Category: Clinical Trials

Do dietary supplements affect the survival of cancer patients?

Do dietary supplements offer advantages or risks to breast cancer patients undergoing chemotherapy?

/ January 9, 2020
Acupuncture

More evidence that acupuncture doesn’t work for chronic pain

Acupuncture is a theatrical placebo whose real history has been retconned beyond recognition. A new systematic review of systematic reviews of acupuncture for chronic pain highlights that conclusion and catalogues the many weaknesses in the design of acupuncture clinical trials.

/ January 6, 2020

Ellura: A Supplement Backed By Evidence

Ellura is a dietary supplement marketed to treat recurrent urinary tract infections. There is promising evidence and a credible mechanism of action, and using it instead of antibiotic prophylaxis could reduce antibiotic resistance.

/ December 24, 2019

The Apple Heart Study

A recent study involving the Apple Watch raises some interesting points about modern clinical trials. It also has some implications and conclusions about screening for atrial fibrillation (a. fib).

/ December 12, 2019
Acupuncture for xerostomia

Spinning a negative acupuncture study: Same as it ever was

Investigators at M.D. Anderson Cancer Center reported the results of a trial of acupuncture for xerostomia (dry mouth) secondary to radiation therapy for head and neck cancers. It was a negative trial, but investigators still tried to spin it as positive, but with a twist. There was a large difference between results found at M.D. Anderson and the second site in China....

/ December 9, 2019
One Million Dollars

Would you pay $1 million to enroll in a phase 1 clinical trial of an “anti-aging” gene therapy?

Libella Gene Therapeutics, LLC made the news last week for announcing a "pay-to-play" trial of its telomerase-based anti-aging gene therapy. What was shocking about the announcement was not that it was a "pay-to-play" trial, given that such trials have become all too common, but rather the price of enrollment: $1 million. Worse, the trial is being conducted in Colombia; the therapy doesn't...

/ December 2, 2019
Clínica 0-19 poster

Clínica 0-19: False hope in Monterrey for DIPG patients (Part 5, A dubious poster is presented)

Clínica 0-19 is a clinic run by Instituto de Oncología Intervencionista (IDOI) Drs. Alberto Swiller and Alberto Garcia in Monterrey Mexico that claims to have a much higher rate of survival for patients with DIPG, a deadly brain cancer, than conventional treatments. Patients come there from all over the world for an unproven concoction of chemotherapy drugs administered directly into arteries feeding...

/ November 18, 2019

The Cleveland Clinic publishes a study claiming to show benefits from functional medicine. It doesn’t.

Last week, the Cleveland Clinic published a study purporting to show that functional medicine improves health-related quality of life. Not surprisingly, on closer examination, there's a lot less to the study than meets the eye, and its results are quite underwhelming.

/ October 28, 2019

“SuperMannan Cures Bladder Infections!” Really?

The ads claim SuperMannan cures bladder infections. The science is a single uncontrolled study of 9 women; its design is a recipe for disaster.

/ October 22, 2019

Electromagnetic healing devices for dogs: Studies show “Meh”

Does a pulsed electromagnetic field device work to help dogs recover from surgery? The answer is below. Spoiler alert: The answer is "probably not".

/ October 11, 2019