Category: Clinical Trials
A Blood Test for Fibromyalgia?
The FM/a test is advertised as a definitive test to diagnose fibromyalgia. It isn't definitive. It is expensive. It has not been shown to change patient outcomes.
Eye Drops for Dry Eyes
I could have chosen a prescription eye drop for my dry eyes. I decided not to. Here's why.
To unblind or not to unblind? That is the question about clinical trials of COVID-19 vaccines
Antivaccine alternative health tycoon Joe Mercola claims that the unblinding of participants in the clinical trials of Moderna and Pfizer COVID-19 vaccines was intended to "blow up the trials" and undermine the science, making it impossible ever to identify long term adverse events. What he's really doing is deceptively oversimplifying complex ethical and scientific issues surrounding these trials in the middle of...
Catgut Acupuncture
Catgut acupuncture is but one example of how acupuncture's basis in pseudoscience provides an infinitely malleable template for fabricated mechanisms of action and feigned health benefits.
Ivermectin is the new hydroxychloroquine
Ivermectin has been touted as a potential antiviral to treat COVID-19 infections. There is no good evidence it is effective.
A New Medication to Combat Obesity
New study in The New England Journal of Medicine finds impressive evidence that weekly semaglutide injections produce clinically significant weight loss as well as many other benefits, approaching the improvements seen with weight loss surgery. Not a definitive answer to obesity, but a very encouraging step in the right direction. Science works.
What the heck happened to John Ioannidis?
John Ioannidis is one of the most published and influential scientists in the world, someone whose skewering of bad medical research we at SBM have frequently lauded over the years. Then the COVID-19 pandemic hit. Since then, Prof. Ioannidis has been publishing dubious studies that minimize the dangers of the coronavirus, shown up in the media to decry "lockdowns," and, most recently,...
The Brownstein protocol is not a proven treatment for COVID-19
Dr. David Brownstein is a "holistic" physician who practices in Dr. Gorski's neck of the woods. Unfortunately, he just wrote a book promoting an unproven protocol involving vitamins, nebulized hydrogen peroxide and iodine, and intravenous ozone to treat COVID-19. There is no evidence that his protocol works, other than a very poor quality case series.
Hepatitis C Vaccine Fails Testing
A vaccine regimen intended to prevent chronic HCV infection was tested in a double-blind placebo-controlled trial. It failed. The incidence of chronic HCV infection was the same in the vaccinated group as in the placebo group.
The effectiveness of zinc and vitamin C on the duration of COVID-19 infections
Vitamin C and zinc have been heralded as treatments for colds for decades, but how well do they work against COVID-19? A new clinical trial provides the answer.