Category: Clinical Trials
New Drug Is Effective for Post-Partum Depression, But There Are Drawbacks
A new drug promises to cure postpartum depression, but it is restricted and patients must be hospitalized for a 60-hour IV infusion.
“Young blood” infusions: same old snake oil
There's no reliable evidence that an infusion of blood plasma from a young donor will benefit an older person, and there are risks, but Ambrosia Health is selling "young blood" infusions for thousands of dollars anyway. The FDA has taken notice.
Dubious for-profit stem cell clinics: Co-opting ClinicalTrials.gov as a marketing tool
Over twenty years ago, cancer quack Stanislaw Burzynski pioneered the abuse of the clinical trial process as a marketing tool to sell his antineoplastons. Now, for-profit stem cell clinics are using ClinicalTrials.gov as a marketing tool for their unproven therapies by listing dubious and scientifically worthless trials in this government database. What can be done?
The FDA’s accelerated drug approval program is failing to protect cancer patients
Drug approval is a process that should be and, for the most part, is rooted in rigorous science. However, there is always a countervailing pressure to approve new drugs rapidly, particularly in cancer. That's why the FDA created the accelerated approval program in the early 1990s. Unfortunately, increasingly this approval process appears to be failing us in oncology. Reform is needed.
Stem Cells for Knee Arthritis
Stem cell treatments for knee arthritis are not yet ready for prime time, but that has not stopped their premature commercialization.
The Best Science from The New England Journal of Medicine
The editor-in-chief of The New England Journal of Medicine has selected a dozen articles published during his tenure that epitomize the best of science-based medicine.
Coca-Cola and Corporate Sponsored Research
A new study reveals that Coca-Cola included restrictive clauses in some research funding contracts. This is a good opportunity to review how such behavior can be stopped.
Chronic Fatigue Syndrome and Rituximab
IV rituximab has been used to treat chronic fatigue syndrome. A large, well-designed new study shows it doesn't work.
Medical Apartheid
Harriet Washington's book tells the dark history of medical experimentation on black Americans. It also reveals broader problems of inequality, poor science, and human failures.
Soothing Your Heart: Does practicing self-compassion have physical and mental health benefits?
Does a recent study demonstrate that being kind to yourself has benefits for your mental and physical health?