Category: Clinical Trials

Rigvir

Rigvir: Another unproven and dubious cancer therapy to be avoided

Alternative cancer clinics have always claimed that their therapies "boost the immune system" to fight cancer. Recently, the Hope4Cancer Institute, a quack clinic in Mexico has added a treatment known as Rigvir to its other offerings. But what is Rigvir? It turns out that it's an import from Latvia, a purported oncolytic virus with a mysterious history that targets cancer specifically for...

/ September 18, 2017
Protein_PCSK9_PDB_2p4e

“New vaccine replaces statins?” Not So Fast!

News reports suggest new drugs may replace statins. PSCK9 inhibitors are useful, but only along with statins in high risk patients not controlled on statins alone, or for patients who can't tolerate statins. They're not about to replace statins.

/ September 5, 2017
Chemotherapy Patient

Alternative medicine kills cancer patients

By definition, alternative medicine has not been shown to be effective or has been shown to be ineffective. Thus, alternative medicine is ineffective against cancer and can best be represented as either no treatment at all or potentially harmful treatment. It is thus not surprising that cancer patients who choose alternative medicine have a higher risk of dying from their cancer. A...

/ August 14, 2017
Sneeze_in_white_hankie

AllerVarx: A Questionable Remedy for Allergic Rhinitis

AllerVarx, a new dietary supplement, claims to relieve nasal allergy symptoms, but the only "evidence" is a single disreputable clinical trial with no control group. There is no reason to try this unproven remedy when there are so many effective remedies offered by mainstream medicine.

/ July 25, 2017
Cancer cell extravasation

Does chemotherapy cause cancer to spread?

Earlier this month, a study was published in Science Translational Medicine that showed how chemotherapy before surgery can stimulate breast cancer invasiveness and invasion under certain circumstances. Not surprisingly, alternative cancer cure mavens everywhere are spinning the study as "proof" that chemotherapy has no benefit and causes only harm (and so you should buy their nostrums instead). Unsurprisingly, the actual results are...

/ July 17, 2017
emergency

Emergency acupuncture!

For whatever reason, acupuncturists and acupuncture believers think that acupuncture can be useful in emergency situations, be they in the field ("battlefield acupuncture," anyone?) or in the ER. They even do studies purporting to show that. This is yet another of such a clinical trial, albeit larger than usual. Guess what? It doesn't really show what it's advertised to show. I explain...

/ July 3, 2017
Yoga

Can mind-body practices “reprogram” our DNA?

A recent systematic review has been touted as demonstrating that "mind-body" practices like yoga can reprogram our DNA. There are several reasons to doubt these claims, not the least of which is the history of bias in past studies on this topic.

/ June 26, 2017
Marijuana bud

Medical marijuana as the new herbalism, part 5: Turning herbalism into science-based medicine

There’s a new clinical trial published in the New England Journal of Medicine showing a beneficial effect due to cannabidiol, a chemical isolated from marijuana, on drug-resistant seizures due to Dravet syndrome. Although there are a fair number of caveats, this is how you begin to turn the herbalism that characterizes medical marijuana advocacy into science-based medicine.

/ May 29, 2017
The editorial staff of The BMJ decides on its next systematic review.

Quackery infiltrates The BMJ

As quackery in the form of "integrative medicine" has increasingly been "integrated" into medicine, medical journals are starting to notice and succumb to the temptation to decrease their skepticism. The BMJ, unfortunately, is the latest to do so. It won't be the last.

/ May 22, 2017
MMR vaccine

Two (now retracted) studies purporting to show that vaccinated children are sicker than unvaccinated children show nothing of the sort

Antivaccine websites have been touting two recently published studies as strong evidence that vaccinated children are less healthy than unvaccinated children. The studies are so flawed that they show nothing of the sort. Even more hilariously, the bottom-feeding predatory open access journal that published them appears to have retracted them.

/ May 11, 2017