Category: Clinical Trials
Federal “right-to-try” over a year later: Still a failure and still about the money (and weakening the FDA)
Federal "right-to-try" legislation was passed and signed into law by President Trump over a year ago. Advocates promised that lots of terminally ill people who were dying then would be saved by having the right to "try" experimental therapies outside of the context of clinical trials. That has not happened. This should come as no surprise, because right-to-try was never about getting...
One reason mouse studies often don’t translate to humans very well
Mouse models are often used as preclinical models of human disease, but the number of drugs that succeed in mice but go on to be approved as a drug for humans is only about one in ten. A new study comparing gene expression in the cells of human brains with those of mouse brains provides new insight into why.
Ebola: Science Is Making Progress
Good news! Research on Ebola has identified a 100% effective vaccine and medications that produce a 90% survival rate.
Vitamin D and Diabetes: Another Case Where Supplementation Sounded Like a Good Idea But Wasn’t
A new study shows vitamin D supplements don't prevent diabetes. But there are still unanswered questions.
For-profit stem cell clinics, universities, and “pay-to-play” clinical trials for autism
Stem cell therapies show great promise, but as yet the vast majority of that promise has not been validated in rigorous clinical trials. Unfortunately, for-profit stem cell clinics are running clinical trials that require patients to pay to be part of it. These trials are not rigorous. Even more unfortunately, it appears that some universities are also running "pay-to-play" clinical trials that...
Vyleesi: New Drug for Hypoactive Sexual Desire in Women
New drug to treat hypoactive sexual desire in women, Vyleesi, is not very effective and has several drawbacks. It is NOT Viagra for women.
Medicare proposal covers acupuncture for back pain study participants: A prelude to full coverage?
Medicare coverage of acupuncture is under consideration. A new proposal would provide coverage to Medicare patients participating in studies of acupuncture for back pain. This research would be used in making a final decision.
New Drug Is Effective for Post-Partum Depression, But There Are Drawbacks
A new drug promises to cure postpartum depression, but it is restricted and patients must be hospitalized for a 60-hour IV infusion.
“Young blood” infusions: same old snake oil
There's no reliable evidence that an infusion of blood plasma from a young donor will benefit an older person, and there are risks, but Ambrosia Health is selling "young blood" infusions for thousands of dollars anyway. The FDA has taken notice.
Dubious for-profit stem cell clinics: Co-opting ClinicalTrials.gov as a marketing tool
Over twenty years ago, cancer quack Stanislaw Burzynski pioneered the abuse of the clinical trial process as a marketing tool to sell his antineoplastons. Now, for-profit stem cell clinics are using ClinicalTrials.gov as a marketing tool for their unproven therapies by listing dubious and scientifically worthless trials in this government database. What can be done?