Category: Clinical Trials

Cerebral angiogram

Clínica 0-19: False hope in Monterrey for brain cancer patients (part 3 of 3)

This is the conclusion of my series on Clínica 0-19, the cancer clinic where Drs. Alberto Siller and Alberto Garcia see patients with DIPG, a deadly brain tumor, whom they treat at Hospital Angeles in Monterrey Mexico with an unproven combination of intra-arterial chemotherapy with up to 11 drugs and a poorly defined dendritic cell immunotherapy. Some people have asked me: What's...

/ July 9, 2018
Clínica 0-19: False hope for DIPG

Clínica 0-19: False hope in Monterrey for DIPG patients (part 1 of 3)

Drs. Alberto Siller and Alberto Garcia run Clínica 0-19 in Monterrey, Mexico, which has become a magnet for patients with diffuse intrinsic pontine glioma (DIPG), a deadly brain cancer. Unfortunately, their treatment is an unproven combination of 11 chemotherapy drugs injected into an artery feeding the brainstem, plus an unknown and unproven "immunotherapy." Of course it all costs $300,000 or more for...

/ June 25, 2018

Prevagen goes P-hacking

Can post-hoc data-dredging produce competent and reliable scientific evidence for Prevagen's claims of memory improvement? The FTC and consumer groups say "no."

/ June 21, 2018
Acupuncture needles

So-Called Alternative Medicine

Edzard Ernst calls it "So-Called Alternative Medicine". This insider's view of SCAM is a new book from an prolific researcher and author.

/ June 14, 2018

Are generic drugs equivalent to brand-name drugs?

Generic drugs cost a fraction of brand-name drugs. What gives us confidence they are equivalent? Science.

/ May 31, 2018

Crowdfunding unproven stem cell treatments: overstated efficacy, unstated risks

Crowdfunding campaigns for unproven stem cell treatments exaggerate the benefits and underemphasize the risks, all the while raising considerable funds and generating social media buzz.

/ May 10, 2018

Essential Oils in the Ambulance

Aromatherapy with essential oils is pseudoscience, backed only with low quality studies guaranteed to show a placebo effect. Their growing popularity warns that better science education is needed.

/ May 9, 2018
Acupuncture needles

PLOS ONE, peer review, and a “crappy” acupuncture study

Meta-analyses can sometimes suffer from the "GIGO problem" (garbage in, garbage out). The publication of a "crappy" acupuncture "network meta-analysis" for acupuncture and chronic constipation illustrates the GIGO problem on steroids and reveals a problem with peer review.

/ May 7, 2018

TIC’D OFF

Two years ago we discussed the TicTocStop, a dental appliance that the inventors assured us would help mitigate the symptoms of Tourette Syndrome. In the intervening years things have...not gone well. This illustrates the need for skepticism regarding questionable medical claims, and the importance of initiatives like AllTrials to ensure the good, the bad, and the ugly research is available to everyone.

/ May 4, 2018

Stem Cell Tourism Comes Home

You used to have to go to China to get ripped off by fraudulent stem cell clinics. Now you can get conned right here at home.

/ May 2, 2018