All posts by Steven Novella

Founder and currently Executive Editor of Science-Based Medicine Steven Novella, MD is an academic clinical neurologist at the Yale University School of Medicine. He is also the host and producer of the popular weekly science podcast, The Skeptics’ Guide to the Universe, and the author of the NeuroLogicaBlog, a daily blog that covers news and issues in neuroscience, but also general science, scientific skepticism, philosophy of science, critical thinking, and the intersection of science with the media and society. Dr. Novella also has produced two courses with The Great Courses, and published a book on critical thinking - also called The Skeptics Guide to the Universe.

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  • Founder and currently Executive Editor of Science-Based Medicine Steven Novella, MD is an academic clinical neurologist at the Yale University School of Medicine. He is also the host and producer of the popular weekly science podcast, The Skeptics’ Guide to the Universe, and the author of the NeuroLogicaBlog, a daily blog that covers news and issues in neuroscience, but also general science, scientific skepticism, philosophy of science, critical thinking, and the intersection of science with the media and society. Dr. Novella also has produced two courses with The Great Courses, and published a book on critical thinking - also called The Skeptics Guide to the Universe.

A doctor interacts with a digital tablet displaying medical data, while a holographic AI robot and various medical charts are projected in the air. Two patients and another medical professional are in the background within a modern, high-tech medical facility.

AI Moral Decision-Making

LLM-based AI models are being increasingly used by physicians to assist clinical decision-making. What might their effect on medical moral reasoning be?

/ September 16, 2026
A man with a leg amputation sits on a bed imagining his missing leg and brain activity, then stands on one leg looking at himself in a mirror in a bright room.

Body Integrity Dysphoria – A Rare and Informative Condition

A fifty-year-old man was admitted through the emergency room with extensive dry ice injuries to his left leg. For two days his doctors tried to save the leg, but the damage was too extensive, so eventually they had to perform a below-knee amputation. During this time the patient also suffered from small strokes due to fat emboli from the damaged leg. After...

/ September 9, 2026
Ivermectin repurposing

Ivermectin and Hydroxychloroquine Six Years On

More than six years after the pandemic arrived and ivermectin and hydroxychloroquine were first touted as COVID cures, the evidence shows more than ever that they don't work.

/ September 2, 2026
A football player in white is tackled by two players in blue uniforms during a game, with a crowd watching in the background.

The NFL and Brain Injury

Last week I wrote about traumatic brain injury (TBI). By coincidence, the BMJ just published a study looking at a type of TBI called chronic traumatic encephalopathy (CTE), which is caused by repeated head injuries over a long period of time, even those not severe enough to cause an acute TBI. They were looking specifically at former NFL football players, because that...

/ August 26, 2026
Diagram showing coup and contrecoup brain injuries: the left shows a head hitting a surface with primary impact to the front brain; the right shows secondary impact at the back of the brain, both highlighted in red.

Preventing Traumatic Brain Injury

Traumatic brain injury (TBI) affects tens of millions of people worldwide each year with about 5 million deaths. For those who survive there is often permanent neurological impairment. TBI is therefore a serious public health issue that needs to be addressed. The largest international study of TBI was recently published in Nature Medicine, providing some insight into how best to approach the...

/ August 19, 2026
A man in a suit holds a large chart with vaccine recommendations while sitting at a desk. Behind him stands another man in a suit. US flags and official emblems are visible in the background.

Trump’s Frontal Assault on Vaccines

On Monday, Donald Trump signed an executive order full of antivax goals. It's a frontal assault on vaccines.

/ August 12, 2026

AI And Pseudoscience

We have to deal with artificial intelligence (AI). We cannot simply dismiss it or criticize it, and we certainly shouldn’t just embrace it without significant skepticism. But I feel it is necessary for any science communicator to do their best to become AI-literate – even if AI itself is not your field of communication. AI now touches everything. For example, increasingly people...

/ August 5, 2026
Colorful boxes of Lemon Twist and Melon Twist e-liquid are displayed on a store shelf. Warning labels and flavors are visible. Other vape products are partially visible on either side.

Negative Health Effects of Vaping

When vaping was first introduced it was marketed mainly as a safer alternative to smoking and as a potential smoking cessation method. But increasingly people who have never smoked are vaping, and now the concern is that vaping is more of a pathway into smoking than one out of it. According to the CDC, about 30% of all adults who vape have...

/ July 15, 2026
A woman holds a letterboard while a boy in a striped hoodie points at it with a pencil. They sit in a peach-colored room, engaged in a communication or learning activity.

NYT Article on Rapid Prompting Method

This is one of those stories that will not go away, and a recent NYT article is fresh evidence of that. The title is: An Autism Breakthrough, or an Illusion? The Fight Over Assisted Spelling.” I always approach such articles cautiously, bracing myself for the cringing experience of reading a non-expert butcher such topics in depressingly predictable ways. This article was not...

/ July 8, 2026
A blue graphic features a mortar and pestle with grapes inside, surrounded by digital and scientific icons. The World Health Organization logo appears at the bottom right.

WHO And The Death of Evidence-Based Medicine

I have long been critical of the World Health Organization’s promotion of dubious treatment methods under the banner of “traditional medicine”. It now has a global strategy to promote what is calls “traditional, complementary and integrative medicine” (TCIM). In my opinion (shared by at least some others) the document is a master class in how to promote medical pseudoscience with the language...

/ July 1, 2026