Mouse models are often used as preclinical models of human disease, but the number of drugs that succeed in mice but go on to be approved as a drug for humans is only about one in ten. A new study comparing gene expression in the cells of human brains with those of mouse brains provides new insight into why.
Stem cell therapies show great promise, but as yet the vast majority of that promise has not been validated in rigorous clinical trials. Unfortunately, for-profit stem cell clinics are running clinical trials that require patients to pay to be part of it. These trials are not rigorous. Even more unfortunately, it appears that some universities are also running "pay-to-play" clinical trials that...
Last week, the largest epidemiological study of its kind was published and concluded, once again, that autism is primarily due to genes and that the environmental component of autism risk is much smaller. Not surprisingly, once again antivaxers didn't want to hear that message.
A new drug promises to cure postpartum depression, but it is restricted and patients must be hospitalized for a 60-hour IV infusion.
The Walsh Institute offers the Walsh protocol for the nutritional treatment of mental illness. This "orthomolecular psychiatry" is not supported by any clinical studies.
This new book addresses the neglected field of research on child and adolescent psychotherapy and does an excellent job of distinguishing treatments that have been proven to work from treatments that are based on pseudoscience.