Category: Neuroscience/Mental Health

Six microscope images show neural tissue with green and red fluorescent staining. Patterns and intensities vary, highlighting differences in cellular structures or experimental conditions across the three paired rows.

In Animal Study, Nanobots Repair Spinal Cords

For my entire career as a neurologist the ability to repair an injured spinal cord has been one of the holy grails. There has always been promising new research that definitely increases our knowledge but doesn’t lead to an effective treatment. This is not for lack of trying – I also remember the period when Christopher Reeve was a tireless promoter of...

/ June 3, 2026

New Review Casts Doubt On Alzheimers Drugs But Is Controversial

There's a lot less than meets the eye to a recent Cochrane review that casts doubt on the efficacy of drugs for Alzheimer's disease.

/ April 22, 2026

Creatine Supplements for Brain Function

There is a long history of supplements marketed to enhance memory, focus, overall cognitive function, and brain health. None of them are backed by quality scientific evidence, and they seem to go through the typical conveyor belt of claims – by the time one claim is collapsing, such as ginkgo biloba, the industry is happy to move on to the next. The...

/ November 19, 2025
A stained cross-section of a brain shows labeled anatomical regions, including "CX" and "CC," with dark and light regions indicating different tissue densities. A scale bar at the bottom right reads 0.5 mm.

Stem Cell Stroke Therapy

We have written quite a bit about fraudulent stem cell clinics. They have followed a typical pattern of overhyping new potential therapies, with some clinics going as far as selling fake stem cell treatments. Stem cells were a likely target – they sound extremely advanced, their potential is easy to understand, and you can use them to justify extreme claims of healing....

/ September 17, 2025
An open box of acetaminophen 500 mg tablets with two blister packs, each containing white oval pills. The box is labeled "24 tablets / oral use" and "extra strength" on a light blue background.

Tylenol and Autism

Earlier this year, HHS secretary RFK Jr. predicted that, “By September, we will know what has caused the autism epidemic and we’ll be able to eliminate those exposures.” Scientists have been researching autism for decades, including what factors are driving changes in diagnostic patterns. Promising such a major breakthrough in just six months is beyond ridiculous, and strongly implies that RFK Jr....

/ September 10, 2025

Lithium and Alzheimer’s Disease

This is an interesting story, which has been all over the news so worthy of covering here. Alzheimer’s disease (AD), the major cause of dementia in humans, is a very complex disease. We have been studying it for decades, revealing numerous clues as to what kicks it off, what causes it to progress, and how to potentially treat it. This has lead...

/ August 13, 2025
A sad woman sits with her hand on her forehead, looking at a laptop. On the screen, a friendly robot asks, "How are you feeling?" in a speech bubble.

AI Therapists – Not Ready for Prime Time

Artificial Intelligence (AI) applications are being rolled out at a furious pace. There is no doubt they are potentially powerful tools, although with flaws and limitations. But one thing that large language models do well is mimic conversational speech. They are great chatbots. For this reason one of the early uses of these chatbots is as AI therapists. There are no hard...

/ July 9, 2025
A hand draws a rising graph with a question mark in a notebook labeled "RESEARCH" on a cluttered desk with charts, a calculator, crumpled papers, coffee, a magnifying glass, and a "REFERENCE" card.

Standards in Behavioral Science

How can we decrease the amount of shoddy science and improve the rigor of research in the behavioral sciences?

/ July 2, 2025
A man in a pink shirt smiles while speaking into a microphone. In the background, two women and a young child sit and smile in a bright, homey room with plants and kitchen items visible.

Real Time Computer Communication

For those with advanced ALS (amyotrophic lateral sclerosis) or certain brainstem strokes, they can be what is referred to as “locked in”. They are mostly paralyzed. A tip of the basilar artery brainstem stroke, for example, can leave one only able to move their eyes. Many with ALS, long before they get to this point, lose the ability to speak because of...

/ June 18, 2025
A digital illustration of a human head in profile shows the brain with highlighted brainstem and cerebellum structures, depicted in orange against a blue background.

Brainspotting is Classic Pseudoscience

Have you heard of brainspotting? It’s been around since 2003 when it was invented out of whole cloth (not “discovered”) by psychotherapist David Grand. It seems to be gaining in popularity recently, so it is worth the SBM treatment. Here is how proponents describe the alleged phenomenon: “Brainspotting makes use of this natural phenomenon through its use of relevant eye positions. This...

/ May 14, 2025