Category: Neuroscience/Mental Health

Thoughts on Neuroplasticity

I recently read a fascinating book, The Brain That Changes Itself by Norman Doidge. He describes case histories and research indicating that the brain is far more malleable than we once thought. We used to think each function was localized to a small area of the brain and if you lost that area of brain tissue the function was gone forever. We once thought...

/ March 18, 2008

Do Antidepressants Work? The Effect of Publication Bias

A recent meta-analysis of the most commonly prescribed antidepressant drugs raises some very important questions for science-based medicine. The study: Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration, was conducted by Irving Kirsch and colleagues, who reviewed clinical trials of six antidepressants (fluoxetine, venlafaxine, nefazodone, paroxetine, sertraline, and citalopram). They looked at all studies...

/ March 12, 2008

Science by press release: A helmet to fight Alzheimer’s disease?

Recently, I’ve had a number of people bring to my attention a news story that has apparently been sweeping the wire services and showing up in all sorts of venues. It is, on its surface, a story of hope, hope for the millions of elderly (and even the not-so-elderly) who are or will be afflicted by that scourge of the mind, memory,...

/ January 28, 2008

Itching and the Imaginary Passenger Brake

The press and government agencies ally to shine a disproportionate amount of publicity on false and improbable medical ideas. (Danger: Congressmen and reporters at work.) The latest was a press release from either the Centers for Disease Control (and prevention? – I’ll get to the “prevention” part later,) or from Kaiser-Permanente Medical Group. Three Bay Area newspapers carried simultaneous articles. The articles...

/ January 24, 2008

Mercury in vaccines as a cause of autism and autism spectrum disorders (ASDs): A failed hypothesis

Mercury. It sounds very, very scary, particularly when you learn it was in some vaccines in the form of thimerosal. Fortunately, science tells us that thimerosal does not cause autism or neurologic injury, contrary to what antivaccinationists tell us.

/ January 7, 2008