Category: Neuroscience/Mental Health

Freeways, autism, and correlation versus causation

I have a love-hate relationship with epidemiology. On the one hand, I love how epidemiology can look for correlations in huge sample sizes, sample sizes far larger than any that we could ever have access to in clinical trials, randomized or other. I love the ability of epidemiology to generate hypotheses that can be tested in the laboratory and then later in...

/ December 20, 2010

Chronic Pain: A Disease in its Own Right

Melanie Thernstrom has written a superb book based on a historical, philosophical, and scientific review of pain: The Pain Chronicles: Cures, Myths, Mysteries, Prayers, Diaries, Brain Scans, Healing, and the Science of Suffering. Herself a victim of chronic pain, she brings a personal perspective to the subject and also includes informative vignettes of doctors and patients she encountered at the many pain...

/ November 9, 2010

PTSD Breakthrough?: It’s Not Science Just Because Someone Says So

It infuriates me when someone misappropriates the word “science” to promote treatments that are not actually based on science. I have just read a book entitled The PTSD Breakthrough: The Revolutionary Science-Based Compass Reset Program by Dr. Frank Lawlis, a psychologist who is the chief content advisor for Dr Phil and The Doctors. There is very little science in the book and...

/ September 21, 2010

Brain Balance

A member of Quackwatch’s Healthfraud discussion list recently reported from a health fair: One booth was a bit of a mystery for me: Brain Balance. “Is your child struggling with ADHD, dyslexia, autism, Asperger’s, Tourette’s, or other related disorders?” A quick glance at their website makes it seem that they may be legitimate. No, a quick glance at their website makes it...

/ September 14, 2010

The final nail in the mercury-autism hypothesis?

PROLOGUE: BAD LUCK AND BAD TIMING Two and a half years ago, very early in the history of this blog, I wrote one of my usual logorrheic (although I prefer the word “comprehensive”) posts entitled Mercury in vaccines as a cause of autism and autism spectrum disorders (ASDs): A failed hypothesis. In that post, I characterized the scientifically discredited notion that the...

/ September 13, 2010

Venous Insufficiency in Multiple Sclerosis

There is an interesting controversy raging in the multiple sclerosis (MS) world that reflects many of the issues we discuss at science-based medicine. Dr. Paolo Zamboni, and Italian vascular surgeon, has now published a series of studies claiming that patients with clinically defined MS have various patterns of chronic cerebrospinal venous insufficiency (CCSVI). Further Dr. Zamboni believes CCSVI is a major cause...

/ August 11, 2010
Elton John, "I'm Still Standing"

The price of opposing medical pseudoscience

When quacks can’t answer with science (which is most commonly), they fall back on their favorite ad hominem attack. They call their critics “pharma shills.” Then they try to silence them by almost any means they view as necessary. Those means can include attempts to get critics fired by going to their bosses and falsely accusing them of serious misdeeds. Dr. Gorski...

/ June 28, 2010

The genetics of autism

Autism and autism spectrum disorders (ASDs) actually represent a rather large continuum of conditions that range from very severe neurodevelopmental delay and abnormalities to the relatively mild. In severe cases, the child is nonverbal and displays a fairly well-characterized set of behaviors, including repetitive behaviors such as “stimming” (for example, hand flapping, making sounds, head rolling, and body rocking.), restricted behavior and...

/ June 14, 2010
Pills

In which Dr. Gorski once again finds himself a target of the “pharma shill” gambit

When quacks can't answer with science (which is most commonly), they fall back on their favorite ad hominem attack. They call their critics "pharma shills." Then they try to silence them by almost any means they view as necessary.

/ June 14, 2010

Certainty versus knowledge in medicine

I don’t want knowledge. I want certainty! — David Bowie, from Law (Earthlings on Fire) If there’s a trait among humans that seems universal, it appears to be an unquenchable thirst for certainty. It is likely to be a major force that drives people into the arms of religion, even radical religions that have clearly irrational views, such as the idea that...

/ June 7, 2010