Tag: Alzheimer’s disease

Fraud, Scientific Rigor, and Alzheimer’s Research

A stunning case of possible fraud in Alzheimer's research reinforces the need for scientific rigor at every level.

/ August 10, 2022

COVID Associated With Neurodegenerative Disorders

COVID infection has been associated with an increased risk of neurodegenerative and neurovascular disease - another reason to keep our eye on this serious illness.

/ June 29, 2022
Alzheimer's Disease

Medicare and Medicaid place restrictions on new Alzheimer’s drug, Aduhelm (aducanumab)

An important decision has been made about a controversial new drug to treat Alzheimer's disease.

/ January 20, 2022

Poor Science Reporting and Premature Enthusiasm

Press releases often outpace the data. Here are some examples of over-enthusiastic reporting on extremely preliminary research.

/ December 21, 2021

FDA’s Decision to Approve Aduhelm (aducanumab) for Alzheimer’s

Criticism of the FDA's decision to approve aducanumab for Alzheimer's disease.

/ July 7, 2021
Alzheimer's Disease

No evidence, no problem: A closer look at the aducanumab approval

Why did the FDA approve aducanumab, a drug that hasn't been shown to work?

/ June 10, 2021
Prions and Creutzfeldt‐Jakob disease

Can mRNA-based COVID-19 vaccines cause prion disease or Alzheimer’s?

Antivax immunologist J. Bart Classen published a paper claiming that mRNA-based COVID-19 vaccines can cause prion disease leading to neurodegenerative diseases like Alzheimer's dementia. What are prions, and can these vaccines cause prion disease? (Spoiler alert: The answer to the second question is almost certainly no. It's speculation based on highly implausible biology.)

/ February 22, 2021
One Million Dollars

Would you pay $1 million to enroll in a phase 1 clinical trial of an “anti-aging” gene therapy?

Libella Gene Therapeutics, LLC made the news last week for announcing a "pay-to-play" trial of its telomerase-based anti-aging gene therapy. What was shocking about the announcement was not that it was a "pay-to-play" trial, given that such trials have become all too common, but rather the price of enrollment: $1 million. Worse, the trial is being conducted in Colombia; the therapy doesn't...

/ December 2, 2019

Mosconi’s Brain Food Diet

Mosconi offers a plan to prevent and treat Alzheimer's and maximize cognitive function in everyone. She claims brain health requires a unique diet, but she fails to make her case. Some of what she says is good standard health advice, but the rest is speculative, not based on good scientific evidence, and sometimes demonstrably wrong.

/ May 29, 2018

Corrigendum. The Week in Review. 03/26/2017

Death from naturopathy. Cows and soldiers have a similar problem. Pseudo-medicines never die. Chiropractic complications. And more.

/ March 26, 2017