Results for: publication bias

Homeopathy Gets a Reality Check in the UK

The House of Commons Science and Technology Committee (STC) has released a report, Evidence Check 2: Homeopathy, in which they recommend that the NHS stop funding homeopathy. The report is a rare commodity – a thoroughly science-based political document. The committee went beyond simply stating that homeopathy does not work, and revealed impressive insight into the ethical, practical, and scientific problems caused...

/ February 24, 2010

Yes, Jacqueline: EBM ought to be Synonymous with SBM

“Ridiculing RCTs and EBM” Last week Val Jones posted a short piece on her BetterHealth blog in which she expressed her appreciation for a well-known spoof that had appeared in the British Medical Journal (BMJ) in 2003: Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials Dr. Val included the spoof’s abstract in her...

/ February 5, 2010

The General Medical Council to Andrew Wakefield: “The panel is satisfied that your conduct was irresponsible and dishonest”

BACKGROUND In my not-so-humble opinion, the very kindest thing that can be said about Andrew Wakefield is that he is utterly incompetent as a scientist. After all, it’s been proven time and time again that his unethical and scientifically incompetent “study” that was published in The Lancet in 1999 claiming to find a correlation between vaccination with MMR and autistic regression in...

/ February 1, 2010

The Tamiflu Spin

I will start, for those of you who are new to the blog, with two disclaimers. First, I am an infectious disease doctor. It is a simple job: Me find bug. Me kill bug. Me go home. I spend all day taking care of patients with infections. My income comes from treating and preventing infections. So I must have some sort of...

/ January 29, 2010

The Mythology of Larry Dossey

A “Double Standard”? Last week I had planned to write a comprehensive critique of a recent comment by Larry Dossey. He had posted it on Val Jones’s betterhealth website in response to Dr. Val’s essay, “The Decade’s Top 5 Threats To Science In Medicine,” originally posted here on SBM. Much of what Dr. Val had identified as the top threats involved recent...

/ January 19, 2010

The life cycle of translational research

I’m a translational researcher. To those of you who aren’t familiar with what that means, it means (I hope) that I study potential therapies in the lab and try to translate them into actual therapies that will cure patients of breast cancer — or, at the very least, improve their odds of survival or prolong survival when cure is not possible. Translational...

/ January 4, 2010

Yet another nail in the coffin of the myth that the MMR vaccine causes autism

Another study, another refutation of the myth that the MMR vaccine causes autism. The same as it ever was. Antivaccine activists won't listen. Also the same as it ever was.

/ December 7, 2009

Conflicts of interest in science-based medicine

Science-based medicine is not perfect. Financial interests, conflicts of interest (COIs), and the pride of individual practitioners can at times undermine it. But it's so much better than any alternative we have tried before. It works, and, although it does so in fits and starts, sometimes all too slowly, it's getting better all the time. Dealing more effectively with COIs will only...

/ November 16, 2009

Pseudo-expertise versus science-based medicine

I am a skeptic. My support for science-based medicine, as important as it is and as much time, sweat, and treasure I spend supporting it, is not the be-all and end-all of my skepticism, which derives from a scientific world view. That’s why, every so often, I like to step back from medicine a bit and look at the broader picture. It’s...

/ November 9, 2009

Yes, But. The Annotated Atlantic and Influenza

Reposted on 11/8 with multiple typo corrections. The Atlantic recently published an article called “Does the Vaccine Matter?.” The quick answer is “yes”. If you want to know more, keep reading. They concluded, based on a narrow interpretation of a small subset of the data, that vaccines probably do not matter. The tone suggests that the vaccine is a vast boondoggle perpetuated...

/ November 7, 2009