Old drugs, new tricks
What does honey bee colony collapse disorder have to do with a potential new cancer treatment? They both relate – in a convoluted manner – to an old antibacterial drug called nitroxoline. True to my devotion as a natural product pharmacologist, I’m proud to say that new life would not have come to nitroxoline had not a fungal natural product called fumagillin...
The risks of CAM: How much do we know?
CAM products and treatments are often sold as "all-benefit, no-risk". While we can highlight the lack of evidence for benefit, even harder can be assessing the risks of CAM.
For shame, Dr. Oz, for promoting Joseph Mercola on your show!
Dr. Oz goes deeper into the quackery well by hosting one of the most notorious quacks of all on his show, Dr. Joe Mercola.
Dr. Oz Embraces Joseph Mercola
At SBM we are highly in favor of physicians and scientists interfacing with the public, using mainstream and new media to promote the public understanding of science and to explain the modern practice of medicine. Now that Dr. Dean Edell has retired (unfortunately) from his radio show, it is probable that Dr. Mehmet Oz has the highest exposure of any media physician....
Why We Get Fat
Journalist Gary Taubes created a stir in 2007 with his impressive but daunting 640-page tome Good Calories, Bad Calories. Now he has written a shorter, more accessible book Why We Get Fat: And What to Do About It to take his message to a wider audience. His basic thesis is that: The calories-in/calories-out model is wrong. Carbohydrates are the cause of obesity...
Simply Raw: Making overcooked claims about raw food diets
This week, I plan on taking on something that’s been sitting near the bottom of my “to do list” for several weeks now. Indeed, readers have been sending me links since November or so to what will be the topic of this week’s post, but something somehow has always managed to push it aside each weekend when the time came to sit...
Cranberry Juice
It always somewhat surprises me how some interventions never seem to die. Theophylline seems to have disappeared in the medical pantheon, but what comes around, goes around. I predict a resurgence of theophylline this century. Despite the recent study that shows, yet again, echinacea has no effect on colds, I predict the study will neither decrease the sales of echinacea nor prevent...
The Good Rewards of Bad Science
All the world sees us In grand style wherever we are; The big and the small Are infatuated with us: They run to our remedies And regard us as gods And to our prescriptions Principles and regimens, they submit themselves. Molière, The Imaginary Invalid (1673)1 The passage above is part of a burlesque doctoral conferment ceremony, where the French playwright Molière (1622-1673)...
1023 2011
The 1023 campaign is a UK based organization whose purpose is to raise awareness of the actual claims of homeopathy. The name is a reference to Avogadro’s number (6.02214179×10^23), which is the number of atoms or molecules of a substance in one unit called a mole. This is an important basic concept in chemistry, for it means that there are a finite...
The Meaning of Secondary Prevention
A November letter to the editor in American Family Physician chastises that publication for misusing the term “secondary prevention,” even using it in the title of an article that was actually about tertiary prevention. I am guilty of the same sin. I had been influenced by simplistic explanations that distinguished only two kinds of prevention: primary and secondary. I thought primary prevention...