Potential New Mechanism of Pain Relief Discovered

The development of drugs and other treatments for specific symptoms or conditions relies heavily on either serendipity (the chance finding of a beneficial effect) or on an understanding of underlying mechanisms. In pain, for example, there are limited ways in which we can block pain signals – such as activating opiate receptors or inhibiting prostaglandins. There are only so many ways in...

/ June 2, 2010

The Weekly Waluation of the Weasel Words of Woo #10

The W^5/2 Hits Double Figyiz! OK, I gotta admit that my friend Orac moved me to render this Special 10th Edition of the W^5/2™ (after a brief hiatus) by mentioning it today in the context of an article that used, er, the topic of our venerable game to great advantage! Some of it is brilliant, unprecedented even: Perhaps most tellingly, the U.S....

/ June 1, 2010

Nine differences between “us and them,” nine straw men burning

I’ll start this post by admitting right up front: I blatantly stole the idea for the title of this post from Mark Crislip’s most excellently infamous post Nine questions, nine answers. Why? Because I really liked that post and felt like it. Also, there seems to be something about the number nine among anti-vaccine zealots: Nine “questions.” Nine circles of hell. Nine...

/ May 31, 2010

Brief Note: The Chiropractic Subluxation is Dead

The General Chiropractic Council, a UK-wide statutory body with regulatory powers, has just published a new position statement on the chiropractic subluxation complex: The chiropractic vertebral subluxation complex is an historical concept but it remains a theoretical model. It is not supported by any clinical research evidence that would allow claims to be made that it is the cause of disease or...

/ May 29, 2010

Andrew Wakefield Fights Back

Dr. Andrew Wakefield was almost single-handedly responsible for frightening the public about a possible association between autism and the MMR vaccine. His alarmist recommendations directly led to lower vaccination rates and a resurgence of measles to endemic levels in the UK. The MMR/autism interpretation of his 1998 article in The Lancet was retracted by 10 of his 12 co-authors. The article itself...

/ May 28, 2010

Lying Liars and their Lying Lies

Carlyle said “a lie cannot live.” It shows that he did not know how to tell them. — Mark Twain There is an infamous hoax from last century called The Protocols of the (Learned) Elders of Zion, an anti-Semitic text purporting to describe a plan to achieve global domination by the Jewish people. Despite the fact that the Protocols is a work...

/ May 27, 2010

Fields, Alternative Medicine, and Physics

In 1996 the American Physical Society, responding to a request from the National Research Council, was asked to examine the potential health hazards of power lines. One of the concerns was that electromagnetic background fields of 2 milligauss might cause cancer (for comparison the earth’s magnetic field is 500 milligauss and fields generated by human physiological processes are hundreds of thousands of...

/ May 27, 2010

Stand up for science-based medicine against anti-vaccine fear mongering in Chicago today

As I’ve pointed out numerous times this week, anti-vaccine loons, led Generation Rescue and a “health freedom” group, have organized an anti-vaccine rally in Grant Park in Chicago from 3 PM to 5 PM CDT. Andrew Wakefield himself will be the keynote speaker, and there will even be some very bad music promoting the anti-vaccine message. The rally, with its wonderfully Orwellian...

/ May 26, 2010

Is Organic Food More Healthful?

In 1952 Martin Gardner, who just passed away this week at the age of 95, wrote about organic farming in his book Fads and Fallacies in the Name of Science. He characterized it as a food fad without scientific justification. Now, 58 years later, the science has not changed much at all. A recent review of the literature of the last 50...

/ May 26, 2010

Red Meat: Is It Hazardous to Health?

Red meat consumption has been linked to diabetes, cardiovascular disease, and several types of cancer (breast, colorectal, stomach, bladder, prostate, and lymphoma). There are plausible mechanisms: meat is a source of carcinogens, iron that may increase oxidative damage, and saturated fat. But correlation and plausibility are not enough to establish causation. Is red meat really dangerous? If so, how great is the...

/ May 25, 2010