Category: Diagnostic tests & procedures
Mouse “avatars”: New predictors of response to chemotherapy?
Over the years, I’ve written a lot about “personalized medicine, mainly in the context of how the breakthroughs in genomic medicine and data pouring in from the Cancer Genome Atlas is providing the raw information necessary for developing truly personalized cancer therapy. The problem, of course, is analyzing it and figuring out how to apply it. Another problem, of course, is developing...
The mammography wars heat up again (2012 edition)
One issue that keeps coming up time and time again for me is the issue of screening for cancer. Because I’m primarily a breast cancer surgeon in my clinical life, that means mammography, although many of the same issues come up time and time again in discussions of using prostate-specific antigen (PSA) screening for prostate cancer. Over time, my position regarding how...
Cancer care in the U.S. versus Europe: Is more necessarily better?
The U.S. is widely known to have the highest health care expenditures per capita in the world, and not just by a little, but by a lot. I’m not going to go into the reasons for this so much, other than to point out that how to rein in these costs has long been a flashpoint for debate. Indeed, most of the...
Keeping the customer satisfied
These days patient satisfaction is becoming more and more important in judging how well hospitals and physicians are doing. Indeed, Medicare reimbursements are linked in part to a patient satisfaction survey administered by the government. The underlying assumption is that patient satisfaction correlates with high quality care, But is that true? I have my doubts. Indeed, there is evidence that, at best,...
A surprising article about “integrative” medicine in The New England Journal of Medicine vs. “patient-centered” care
The New England Journal of Medicine (NEJM) is published on Thursdays. I mention this because this is one of the rare times where my owning Mondays on this blog tends to be a rather large advantage. Fridays are rotated between two or three different bloggers, and, as awesome as they are as writers, bloggers, and friends, they don’t possess the rabbit-like speed...
Is gluten the new Candida?
Celiac disease and non-celiac gluten sensitivity are very different things. The former has a large, visible, well-understood scientific foundation that is lacking in the latter.
Re-thinking the Annual Physical
Please note: the following refers to routine physicals and screening tests in healthy, asymptomatic adults. It does not apply to people who have been diagnosed with diseases, who have any kind of symptoms or signs, or who are at particularly high risk of certain specific diseases. Throughout most of human history, people have consulted doctors (or shamans or other supposed providers of...
Applied Kinesiology: Nonsense on Full Automatic
I start these entries about a week before their due date, and when I saw Dr Hall’s Applied Kinesiology (AK) post from Tuesday, I thought the heck, there goes my post for Friday. After reading Harriet’s post, I think mine will be both complementary and alternative, and perhaps even integrative, to her entry. I do have one quibble with her post. She...
IgG Food Intolerance Tests: What does the science say?
I spend a lot of time as a pharmacist discussing side effects and allergies to drugs. For your own safety, I won’t recommend or dispense a drug until I know your allergy status. I don’t limit the history to drugs—I want to know anything you’re allergic to, be it environmental, food, insects, or anything else. Allergies can create true therapeutic challenges: We...
Blind-Spot Mapping, Cortical Function, and Chiropractic Manipulation
Steven Novella recently wrote about so-called “chiropractic neurology” and its most outspoken proponent, Ted Carrick. In 2005 I published an article in The Scientific Review of Alternative Medicine (Vol 9, No 1, p. 11-15) entitled “Blind-Spot Mapping, Cortical Function, and Chiropractic Manipulation.” It was an analysis of a study Carrick had published. Carrick read a shorter, popularized version of my critique in Skeptical...