Category: Clinical Trials

Abigail Shrier vs. trans teens

Abigail Shrier’s Irreversible Damage: A Wealth of Irreversible Misinformation

A critical, science-based analysis of Abigail Shrier's book Irreversible Damage.

/ July 2, 2021
Ivermectin

Ivermectin is the new hydroxychloroquine, take 2

A few months ago, Scott Gavura wrote about how the veterinary deworming drug ivermectin has become the new hydroxychloroquine in that it is being promoted as a highly effective treatment against COVID-19—and by many of the same people who previously promoted HCQ—despite evidence that is, at best very weak and at worst completely negative. Unfortunately, with the publication of two new and...

/ June 21, 2021
Alzheimer's Disease

No evidence, no problem: A closer look at the aducanumab approval

Why did the FDA approve aducanumab, a drug that hasn't been shown to work?

/ June 10, 2021

A Blood Test for Fibromyalgia?

The FM/a test is advertised as a definitive test to diagnose fibromyalgia. It isn't definitive. It is expensive. It has not been shown to change patient outcomes.

/ May 11, 2021

Eye Drops for Dry Eyes

I could have chosen a prescription eye drop for my dry eyes. I decided not to. Here's why.

/ May 4, 2021
Pfizer/BioNTech COVID-19 vaccine

To unblind or not to unblind? That is the question about clinical trials of COVID-19 vaccines

Antivaccine alternative health tycoon Joe Mercola claims that the unblinding of participants in the clinical trials of Moderna and Pfizer COVID-19 vaccines was intended to "blow up the trials" and undermine the science, making it impossible ever to identify long term adverse events. What he's really doing is deceptively oversimplifying complex ethical and scientific issues surrounding these trials in the middle of...

/ April 26, 2021
Acupuncture for xerostomia

Catgut Acupuncture

Catgut acupuncture is but one example of how acupuncture's basis in pseudoscience provides an infinitely malleable template for fabricated mechanisms of action and feigned health benefits.

/ April 22, 2021

Ivermectin is the new hydroxychloroquine

Ivermectin has been touted as a potential antiviral to treat COVID-19 infections. There is no good evidence it is effective.

/ April 15, 2021

A New Medication to Combat Obesity

New study in The New England Journal of Medicine finds impressive evidence that weekly semaglutide injections produce clinically significant weight loss as well as many other benefits, approaching the improvements seen with weight loss surgery. Not a definitive answer to obesity, but a very encouraging step in the right direction. Science works.

/ April 6, 2021
John Ioannidis with Laura Ingraham on Fox News

What the heck happened to John Ioannidis?

John Ioannidis is one of the most published and influential scientists in the world, someone whose skewering of bad medical research we at SBM have frequently lauded over the years. Then the COVID-19 pandemic hit. Since then, Prof. Ioannidis has been publishing dubious studies that minimize the dangers of the coronavirus, shown up in the media to decry "lockdowns," and, most recently,...

/ March 29, 2021