Category: Basic Science
Do mRNA vaccines produce harmful “junk proteins” that “gunk up” the cell and cause unintended “off-target” immune responses?
A new study is making the rounds in the antivax crankosphere. The study found that the modified mRNA used in the Pfizer vaccine can cause a frame shift (to be explained) that results in the production of proteins besides the intended spike protein. The findings are, as you probably guessed, a big nothingburger compared to how they are being spun.
Complete Human Embryo Model Made From Stem Cells
Researchers create an embryo model from human embryonic stem cells.
Evidence-based medicine vs. basic science in medical school
Last week Dr. Vinay Prasad wrote a Substack arguing that medical students should learn the principles of evidence-based medicine before basic science.This is a recipe for amplifying the main flaw in EBM that science-based medicine was meant to correct, and Dr. Prasad's arguments would have been right at home on an integrative medicine blog. [Note ADDENDUM.]
Part of a Complete Breakfast
Infection control. When one adheres to compliance it is effective. Like masks and COVID 45.
After 15 years of SBM: Lessons learned and what the future holds
Last week, Dr. Novella discussed what SBM has accomplished over the last 15 years. I'm going to discuss lessons learned, what has changed, and remaining huge challenges. Unfortunately, after the pandemic, our position in 2022 reminds me even more than ever of Aragorn at the Black Gate of Mordor, but that does not mean things are hopeless.
Do COVID-19 vaccines cause “turbo cancer”?
Over the last several months, antivaxxers have been claiming that COVID-19 vaccines cause "turbo cancer", cancers (or cancer recurrences) of a particularly aggressive and fast-growing variety diagnosed in younger and younger patients. "Turbo cancer" is not a thing, and the evidence cited is as weak as any antivax "evidence", including anecdotes and misinterpretation of epidemiology.
Serologies
“You keep using those words: positive serology. I do not think it means what you think it means.”
Improving how the NIH decides which grants to fund: Reality vs. conspiracy
Last week, the United States National Institutes of Health (NIH) announced a plan to decrease the problem of reputational bias in grant funding. I couldn't help but contrast how hard the NIH tries to use the most rigorous scientific criteria to decide whose grants to fund with the conspiracy theory that Anthony Fauci personally doles out NIH dollars like a mob boss...
How the “Don’t take this medication with grapefruit juice” warning originated
How a chance discovery by one scientist improved the safety of consumers worldwide.
Madonna !?!
Remembering the old days of Madonna, courting, and naloxone use.