Category: Basic Science

3-BP: A "safe" and "nontoxic" cancer cure targeting the Warburg effect that quite possibly killed three cancer patients in Germany.

3-Bromopyruvate: The latest cancer cure “they” don’t want you to know about

Why is it that whenever naturopaths and other quacks embrace a new "cancer cure," somehow "they" (whoever "they" are) don't want you to know about it? In this case, it's 3-BP, an actual experimental drug that shows some promise but is by no means ready for prime time (or FDA approval) yet.

/ August 15, 2016
Mass spectrometer

Deconstructing the Conspiracy of Deliberate Poisoning of US Municipal Water

Heavy metals here, there, everywhere… One of the key narratives among the supporters and practitioners of complementary and alternative medicine (CAM), particularly those with a conspiratorial world-view, is the claim that vast portions of the US general populous is being deliberately poisoned by certain corporations, special-interest groups, invested individuals, and the US government. Some of these supporters and practitioners go as far...

/ July 31, 2016

Acupuncture and Endorphins: Not all that Impressive

I was reading, and deconstructing, a particularly awful bit of advice for acupuncture by Consumer Reports. It was the same old same old, but it was the source that made it particularly awful. I expect more from Consumer Reports than the uncritical regurgitation of the standard mythical acupuncture narrative. The report included the quote One possible reason for the benefits of acupuncture:...

/ July 22, 2016

The Gene: An Intimate History

Six years ago I reviewed Siddhartha Mukherjee’s book The Emperor of All Maladies: A Biography of Cancer. It was hands-down one of the best books I have ever read on a medical topic. Now he’s done it again. His new book is titled The Gene: An Intimate History. Mukherjee is a superb writer. Much of what I said about his first book...

/ July 19, 2016
Is this a PVS structure or something else?

The Primo Vascular System: The N-rays of Acupuncture?

Acupuncture meridians and acupoints are imaginary until proven otherwise. Anatomists have never been able to detect them by microscopy or autopsy, and they are not mentioned in anatomy textbooks. For decades, acupuncturists have been trying to prove that their pre-scientific belief system is grounded in scientific reality. Now they are telling us that acupuncture meridians and acupoints have been discovered in the...

/ June 7, 2016
Cancer cell immunofluorescence

Is there a reproducibility “crisis” in biomedical science? No, but there is a reproducibility problem

Reproducibility is the key to scientific advancement. It has been claimed that we suffer from a "reproducibility crisis," but in reality it is a chronic problem in reproducibility. Here we will look at the scope of the problem and strategies to address it.

/ June 6, 2016
Integrative medicine

“Integrative” medicine versus “alternative” medicine

I’ve written a lot about the language issue with respect to alternative medicine. As I like to put it (at least in shortened form), first there was quackery. Quacks did not like that name at all, and thus was born alternative medicine. And the quacks did think it good—for a while. There was a problem, however. “Alternative” medicine implied (correctly, of course)...

/ May 15, 2016
Skin microbiome large

Vaginal Seeding. Ew. That’s nuts. Hmmm, interesting.

Sometimes a headline will cause me to run through a series of reactions in rapid sequence. For example “Mothers facing C-sections look to vaginal ‘seeding’ to boost their babies’ health”: Early studies show that swabbing a mother’s vagina and transferring it to her baby’s mouth, eyes and skin may stimulate microbiome development similarly to babies born naturally – and protect it from...

/ May 13, 2016

Sharks Get Cancer, Mole Rats Don’t: Clues to Understanding Cancer

We think of cancer as caused by mutations. Mutations are necessary, but not sufficient, to cause cancer. New research indicates that it’s the body’s response to mutant cells that determines whether cancer will develop. James S. Welsh, MD, a radiation oncologist and researcher, has written a book on the immunology of cancer, Sharks Get Cancer, Mole Rats Don’t: How Animals Could Hold...

/ May 3, 2016
Where's the sauna detox?

NCCIH Strategic Plan 2016-2021, or: Let’s try to do some real science for a change

It’s no secret that we at Science-Based Medicine (SBM) are not particularly fond of the National Center for Complementary and Integrative Health (NCCIH). Formerly known as the National Center for Complementary and Alternative Medicine (NCCAM) and before that the Office of Alternative Medicine, NCCIH has been the foremost government agency funding research into quackery for the last 24 years, and, of course,...

/ April 4, 2016