Tag: plausibility
Professor Gives Grades to Alternative Medicine
Edzard Ernst assigns a grade to 150 alternative medicine modalities, evaluating plausibility, efficacy, safety, cost, and risk/benefit balance. A very useful reference.
Gary Null’s Attack on SBM
Gary Null's fact- and logic-free attack on SBM.
Spinal Manipulation for Back and Neck Pain: Does It Work? Annotated.
Spinal Manipulation for Back and Neck Pain: Does It Work? You would think it does if you read the article but not if you actually read the literature.
Homeopathy and Plausibility
The fundamental concept of science-based medicine (SBM) is that medical practice should be based upon the best available science. This may seem obvious, but there are many important details to its application, such as the relationship between clinical and basic science. Clinical claims require clinical evidence, but clinical evidence can be tricky and is often preliminary. It is therefore helpful (I would...
Plausibility in Science-Based Medicine
A question that arises often when discussing the optimal role of science in medicine is the precise role of plausibility, or prior probability. This is, in fact, the central concept that separates (for practical if not philosophical reasons) science-based medicine (SBM) from evidence-based medicine (EBM). The concept featured prominently in the debate between myself and Dr. Katz at the recent Yale symposium...
When Further Research Is NOT Warranted: The “Wisdom of Crowds” Fallacy
Most scientific research studies have at least one thing in common: the conclusion section ends with, “further research is warranted.” I’d say it’s about as common as the “talk to your doctor” disclaimer in TV ads for pharmaceutical products. And in a way, they both serve the same purpose. They’re a “CYA” move. What does “further research is warranted” mean in plain...
Why Scientific Plausibility Matters
Why plausibility must play a central role in scientific medicine.