Tag: genome

One reason mouse studies often don’t translate to humans very well

Mouse models are often used as preclinical models of human disease, but the number of drugs that succeed in mice but go on to be approved as a drug for humans is only about one in ten. A new study comparing gene expression in the cells of human brains with those of mouse brains provides new insight into why.

/ August 26, 2019

The Gene: An Intimate History

Six years ago I reviewed Siddhartha Mukherjee’s book The Emperor of All Maladies: A Biography of Cancer. It was hands-down one of the best books I have ever read on a medical topic. Now he’s done it again. His new book is titled The Gene: An Intimate History. Mukherjee is a superb writer. Much of what I said about his first book...

/ July 19, 2016