Tag: cholesterol

Cholesterol le grand bluff

The Movie “Cholesterol: The Great Bluff” Is an Exercise in Denialism

The movie "Cholesterol: The Great Bluff" claims that we have been lied to: cholesterol doesn't cause heart disease and statins are harmful. It is biased and misleading. The people interviewed in the movie are denialists who don't accept the clear evidence for the role of blood cholesterol levels and the benefits of statins.

/ September 12, 2017
Protein_PCSK9_PDB_2p4e

“New vaccine replaces statins?” Not So Fast!

News reports suggest new drugs may replace statins. PSCK9 inhibitors are useful, but only along with statins in high risk patients not controlled on statins alone, or for patients who can't tolerate statins. They're not about to replace statins.

/ September 5, 2017
Red Yeast Rice

Statins beat supplements

Red yeast rice supplements have poor quality control and there's no clear evidence they do anything beneficial. So why take it?

/ August 24, 2017
CholesterolFoods

The Skinny on Saturated Fat

The bottom line is that there are trade-offs and complexities when it comes to biology. A high carbohydrate diet is a risk factor for many diseases, and this is highly genetically variable. Types of sugar matter, weight matters, exercise matters, and genetics matter. The same is true of fat.

/ June 28, 2017
benecol-product-image

A review of Benecol, a plant-stanol margarine

Most nutraceuticals don't really work as advertised. For the most part, Benecol pretty much does. But is it worth it?

/ December 27, 2016
In rosuvastatin we trust?

Statins for everyone? Not so fast.

People love the idea of preventive medicine. Preventing a disease, before it occurs, seems intuitively obvious. But when it comes to taking medicine to prevent a disease before it occurs, people tend to be much less comfortable. Not only are there the concerns about the “medicalization” of healthy people, there are good questions about benefits, risks, and costs. Cardiovascular disease will kill...

/ April 7, 2016
The statin hypothesis is that statins reduce crdic risk more than can be explained by the reduction in LDL cholesterol. That hypothesis has been overturned y a new study.

Update on Cholesterol and Statins

The consensus of mainstream medicine is that a high blood level of LDL cholesterol is a major risk factor for cardiovascular disease and that lowering high levels can help with prevention and treatment. Statins have been proven effective for lowering cholesterol levels and for decreasing cardiovascular and all-cause mortality. I recently wrote about the new guidelines for statin therapy. Currently half of...

/ July 7, 2015

New Cholesterol Guidelines

On November 15, the American College of Cardiology and the American Heart Association released an updated guideline for the use of statins to prevent and treat atherosclerotic cardiovascular disease (ASCVD). The full report is available online. It has already generated a lot of controversy. The news media have characterized it as a “huge departure” from previous practice and have trumpeted that it...

/ November 26, 2013

Eggs and Atherosclerosis

The headline of a recent Los Angeles Times article is, “No yolk: eating the whole egg as dangerous as smoking?” The question mark is meant to convey uncertainty or surprise, or perhaps both. The article represents much of what is wrong with science and health reporting by mainstream media. The news report is based upon an article published in Atherosclerosis – Egg...

/ August 15, 2012

Red Yeast Rice and Cholesterol

While much of CAM is ridiculous or implausible, herbal remedies are an exception. Plants produce pharmacologically active substances; in fact, the science of pharmacology grew out of herbalism. Some herbal remedies have not been scientifically tested, but others have been tested and are clearly effective. Nevertheless, these are seldom if ever the best choice for treatment. One natural remedy stands out. Red...

/ July 24, 2012