The final nail in the coffin for the antivaccine rallying cry “Too many too soon”?
There are some weeks when I know what my topic will be—what it must be. These are weeks in which the universe gives the very appearance of handing to me my topic for the week on the proverbial silver platter with a giant hand descending from the clouds, pointing at it, and saying, “Blog about this, you idiot!” Usually, it’s because a...
More shameless self-promotion that is, I hope, at least entertaining
Three weeks ago, I gave a talk to the National Capital Area Skeptics at the National Science Foundation in Arlington, VA. The topic was one near and dear to my heart, namely quackademic medicine. I was informed the other day that the video had finally been posted. Unfortunately, there were some problems with the sound in a couple of places, which our...
Behold the spin! What a new survey of placebo prescribing really tells us
One of the recurring topics here at SBM is the idea of the placebo: What it is, what it isn’t, and how it complicates our evaluation of the scientific evidence. One my earliest lessons after I started following this blog (I was a reader long before I was a writer) was that I didn’t understand placebos well enough to even describe them...
Evidence Thresholds
Defenders of science-based medicine are often confronted with the question (challenged, really): what would it take to convince you that “my sacred cow treatment” works? The challenge contains a thinly veiled accusation — no amount of evidence would convince you because you are a nasty skeptic. There is a threshold of evidence that would convince me of just about anything, however. In...
What Does ND Mean?
Chronic Lyme disease almost certainly does not exist, but a growing number of doctors are diagnosing and treating it with long-term antibiotics and other remedies. They are known as LLMDs (“Lyme Literate” medical doctors). This subject has been covered repeatedly on Science-Based Medicine, here, here, here, here, and elsewhere. I have a correspondent who joined a Yahoo group for Lyme disease (Northern...
Once more into the screening breach: The New York Times did not kill your patient
Dr. George Lombardi thinks that he could have saved a patient from dying of prostate cancer if a prostate specific antigen test had been done. Is he right? Probably not.
A little Swedish interlude
I’ve been remiss in not mentioning this; so I’ll try to make up for it now. Recently, I did an interview on the Skeptikerpodden, a Swedish podcast. Unless you speak Swedish, you won’t understand much else of the podcast, but don’t worry. I don’t speak Swedish either, which is why my interview is in English. It starts at around the 44:00 mark.
Comprehending the Incomprehensible
Medicine is impossible. Really. The amount of information that flows out the interwebs is amazing and the time to absorb it is comparatively tiny. If you work, sleep and have a family, once those responsibilities are complete there is remarkably little time to keep up with the primary literature. I have made two of my hobbies (blogging and podcasting) dovetail with my...
At Your Own Risk
In 2011, Americans spent some $30 billion on dietary supplements. Yet, except for the industry itself and a few politicians and “health freedom” advocates, you’d be hard pressed to find anyone (who’s given it some thought) of the opinion that dietary supplement regulation is adequate. Three recent reports, two from the government and one from a newspaper, demonstrate why this near-universal conclusion...
Clinical Decision-Making Part III
How do doctors make clinical decisions to arrive at a diagnosis? Part 3 of a 3-part series.

