All posts by David Weinberg

David Weinberg is a full-time academic vitreoretinal surgeon, and professor of ophthalmology at the Medical College of Wisconsin, Milwaukee. His interest in the less-than-science-based aspects of medicine was sparked by inquiries from his patients. Investigation their questions led to his discovery of numerous grandiose claims for implausible, unproven treatments of potentially blinding eye diseases. All opinions expressed by Dr. Weinberg are his alone, and do not represent those of his employer or any other organization with which he is affiliated.

Hydroxychloroquine, retinal toxicity, and COVID-19

Hydroxychloroquine is being promoted as a treatment or prevention for COVID-19 based on questionable evidence. The long-term impact of hydroxychloroquine on the retina introduces another reason to be cautious about its use outside of clinical trials.

/ May 1, 2020

The p-hackers toolkit

P-hacking is a common and persistent problem in research, with impacts on the scientific literature, reporting, and practice in medicine. But what is it, really?

/ April 30, 2020

Patients Blinded by Stem Cell Therapy: FDA (and consumers) win a legal victory!

The Food and Drug Administration just won a court case supporting the agency's ability to regulate stem cell clinics that rely on client-derived adipose tissues. This is a win for consumer protection, though too late to help those already harmed.

/ June 10, 2019

Patients blinded by stem cell therapy: an update

An update on the tragic results of unproven stem cell treatments to treat macular degeneration.

/ May 10, 2019

Macular Degeneration, Genes, and Grandma’s Vitamins: To test or not to test?

Is genetic testing necessary to optimize treatment for patients with a potentially blinding eye disease? The stakes are high and the answer depends on which of the two feuding, financially-conflicted groups you believe. In the end, the best evidence wins!

/ March 30, 2018

Patients blinded by stem cell therapy: more egregious than you imagined

Three patients were treated with a slurry of stem cells and blood products, in both eyes, on the same day. Could the outcome, three patients becoming legally blind, have been foreseen? Probably.

/ April 15, 2017

Stem Cell Tourism for Eye Disease: No Passport Required

Stem cell clinics outside the United States, and outside the jurisdiction of the U.S. regulations, have flourished and the pursuit of treatment at these centers has been called “stem cell tourism.” Seekers of unproven stem cell therapies no longer need to look outside the U.S. Paul Knoepfler, a stem cell researcher and leading advocate for the responsible use of stem cell technology,...

/ October 16, 2016

You be the judge

Jann Bellamy recently recapped her experience attending a meeting sponsored by her local Healing Arts Alliance. As you re-read her article pay particular attention to the language used by the Alliance to describe themselves and the treatments they offer. For me, there is one word that really stands out. It is emblematic of the attitude of the complementary and alternative medicine community....

/ November 29, 2013

Anti-VEGF treatment of Macular Degeneration: Science-Based Success

Let's celebrate some good science with a story about some evidence-based treatments for macular degeneration!

/ October 25, 2013

Andrew Weil Flirts with Evidence Based Medicine

Andrew Weil, MD, pops up quite frequently on SBM, most recently in this entry by Harriet Hall, so I will not spend much space introducing him. An excellent biography and critique of Dr. Weil was written by Arnold Relman, former Editor of the New England Journal of Medicine. It is over a decade old, but contemporary to some of the events described...

/ December 7, 2012