Category: Clinical Trials

A Different Perspective: Placebo, SCAM, and Advertising

Summertime, time, time Child, the living’s easy. Fish are jumping out And the handicap, Lord Handicaps high, Lord so high ~ Janis Joplin It is summer. Time for the kids and the outside, not the computer. What follows is a summertime blog entry, for which I admit to feeling guilty for the comparatively little time I have spent on it, but as...

/ August 9, 2013

Integrative Medicine Invades the U.S. Military: Part Three

Nobody seems to know exactly how to define “integrative medicine” (“IM”) or to demonstrate what it does that is superior to the “conventional” kind. There is a lot of talk about addressing the “whole person” and not just the disease, patient-centeredness and the like, all of which are already aspects of conventional medicine. But, however defined, the central idea seems to be...

/ August 8, 2013

The difference between science-based medicine and CAM

There is a huge difference between science-based medicine (SBM) and so-called "complementary and alternative medicine" (CAM) or, as it's increasingly called, "integrative medicine." That difference is that SBM changes with new science. The change might be messier and slower than we would like, but eventually science and evidence win out.

/ July 29, 2013

Integrative Medicine Invades the U.S. Military: Part One

Integrative medicine proponents claim superiority over physicians practicing “conventional” medicine. (Which I will refer to as “medicine” so as not to buy into integrative medicine’s implied claim that medicine can be practiced with two separate standards.) While conceding that medicine is good for treating conditions like broken arms and heart attacks, physicians who purport to practice integrative medicine argue it ignores “the...

/ July 25, 2013

Stanislaw Burzynski: The Early Years, part 1

It’s been a week now since I got back from TAM, where Bob Blaskiewicz and I tag-teamed a talk about a man who has become a frequent topic of this blog, namely Stanislaw Burzynski. I’ve been meaning to come back to the topic of Burzynski, but from a different angle. There hasn’t been much in the way of news lately other than...

/ July 22, 2013

Do clinical trials work? It depends on what you mean by “work”

Introduction (Skip to the next section if you want to miss the self-referential blather about TAM.) As I write this, I’m winging my way home from TAM, crammed uncomfortably—very uncomfortably—in a window seat in steerage—I mean, coach). I had been thinking of just rerunning a post and having done with it, sleeping the flight away, to arrive tanned, rested, and ready to...

/ July 15, 2013

Homeopathy Ramblings

There needs to be a SCAM index, some quantitative tool, a formula for ranking the SCAMs, so one SCAM could reign supreme, to be definitely declared the the goofiest of all SCAMs. Perhaps (number of adherents)x(number of Pubmed publications)x(age of SCAM) all divided by a plausibility factor. Homeopathy would win and any SCAM index that did not rank homeopathy at number one...

/ June 28, 2013

Coenzyme Q10 for heart failure: The hype and the science

Could a product sold as a dietary supplement really be delivering the benefits that advocates have claimed for decades? That’s what you might be wondering about coenzyme Q10, following recent stories like: The energy-boosting supplement that could HALVE the number of deaths from heart failure screamed The Daily Mail. It’s Official: Coenzyme Q10 Improves Heart Failure Survival from the “orthomolecular” advocates AOR....

/ June 20, 2013

Two Viewpoints

Most of what I read professionally is directed towards reality-based medicine. I spend my professional energies thinking about the application of reality to killing various and sundry microscopic pathogens. The conceptual framework I use, and that used by others in medicine, does not concern itself with the application of the Supplements, Complementary and Alternative Medicines that occupy the attention of this blog....

/ June 14, 2013

BBC Panorama investigates Stanislaw Burzynski

Last week, I reviewed a long-expected (and, to some extent, long-dreaded) documentary by Eric Merola, a filmmaker whose talent is inversely proportional to his yen for conspiracy, pseudoscience, and quackery. Through a quirk of fate that couldn’t have worked out better if I had planned it myself, a long-expected investigation of the Burzynski Clinic by the BBC aired on its venerable news...

/ June 10, 2013