Category: Clinical Trials
What’s in a name?: NCCAM tries to polish a turd
What’s in a name? that which we call a rose By any other name would smell as sweet; So Romeo would, were he not Romeo call’d, Retain that dear perfection which he owes Without that title. Romeo, doff thy name, And for that name which is no part of thee Take all myself. William Shakespeare, Romeo and Juliet, Act II, Scene 2...
More Dialogs
There is no alternative medicine. There is only scientifically proven, evidence-based medicine supported by solid data or unproven medicine, for which scientific evidence is lacking. JAMA Just just because there are flaws in aircraft design that doesn’t mean flying carpets exist. Ben Goldacre Wiser heads than I have commented on “Invitation to a Dialogue: Alternative Therapies” in The New York Times. So...
A formal request for retraction of a Cancer article
I am formally requesting that Cancer retract an article claiming that psychotherapy delays recurrence and extends survival time for breast cancer patients. Regardless of whether I succeed in getting a retraction, I hope I will prompt other efforts to retract such articles. My letter appears later in this post. In seeking retraction, I cite the standards of the Committee on Publication Ethics...
CureCrowd – Crowdsourcing Science
A new website came to my attention that promises to “Discover what truly works.” The idea is to essentially crowdsource anecdotal reports about what treatments work for specific conditions. This is an interesting idea, that can harness the power of information flow over the internet to do what is essentially an observational, uncontrolled, and unscientific study about treatment effects. At its best,...
Cochrane Reviews: The Food Babe of Medicine?
There are two topics about which I know a fair amount. The first is Infectious Disease. I am expert in ID, Board Certified and certified bored, by the ABIM. The other, although to a lesser extent, is SCAMs. When I read the literature on these topics, I do so with extensive knowledge and, in the case of ID, 30 years of clinical...
The Compassionate Freedom of Choice Act: Ill-advised “right to try” goes federal
Not too long ago, I expressed alarm at a series of bills that were popping up like so much kudzu in various state legislatures, namely “right to try” bills. Both Jann Bellamy and I warned that these bills gave a false illusion of hope to patients with terminal illnesses. Basically, these laws claim to grant the “right” of patients with terminal illnesses...
Curing Hepatitis C: A Success Story and a Price Tag
Previously incurable, hepatitis C now has a treatment. A very, very expensive treatment. But there is hope for acutely and chronically infected people.
Gluten-free skin and beauty products: Extracting cash from the gullible
Gluten-free doesn't make sense for a lot of diets. Except for lip balm and toothpaste, it makes an order of magnitude less sense for beauty products.
New evidence, same conclusion: Tamiflu only modestly useful for influenza
Does Tamiflu have any meaningful effects on the prevention or treatment of influenza? Considering the drug’s been on the market for almost 15 years, and is widely used, you should expect this question has been answered after 15 flu seasons. Answering this question from a science-based perspective requires three steps: Consider prior probability, be systematic in the approach, and get all the...

