Category: Basic Science
A brief note on killing cancer cells in a dish
I am taking the Memorial Day holiday off. I will return next week (or even earlier if something comes up that I can’t resist blogging about). In the meantime, here’s a general principle that needs to be remembered in cancer research: I would also add to that list: So does bleach. So does acid. So does alkali. So does pouring the media...
Angelina Jolie, radical strategies for cancer prevention, and genetics denialism
I had been debating whether to blog about Angelina Jolie’s announcement last week in a New York Times editorial entitled My Medical Choice that she had undergone bilateral prophylactic mastectomy because she had been discovered to have a mutation in the BRCA1 gene that is associated with a very high risk of breast cancer. On the one hand, it is my area...
Undermining the regulation of stem cell therapies in Italy: A warning for the future?
Stem cells are magical. At least, if you listen to what docs and “practitioners” who run stem cell clinics in various parts of the world, usually where regulation is lax and money from First World clientele is much sought after, that’s what you could easily come to believe. Unfortunately, it’s not just Third World countries in which “stem cell clinics” have proliferated....
A Skeptic’s Guide to the Mind
In his first book, On Being Certain: Believing You Are Right Even When You’re Wrong, neurologist Robert Burton showed that our certainty that we are right has nothing to do with how right we are. He explained how brain mechanisms can make us feel even more confident about false beliefs than about true ones. Now, in a new book, A Skeptic’s Guide...
Uneasy Lies the Head That Wears the Flu
Infectious diseases (ID), as those who read my not-so-secret other blog know, is without a doubt the most interesting speciality of medicine. Every interesting disease is infectious in etiology. What is cool about ID is that it has connections into almost every facet of human culture and history. I note that at some point I have gone from being the young whippersnapper...
Doves, Diplomats, and Diabetes
In the past I have criticized evolutionary medicine for its tendency to rely on unverifiable “Just-So Stories,” but a new book has helped me appreciate what the best kind of evolutionary thinking can contribute to our understanding of medicine. Doves, Diplomats, and Diabetes: A Darwinian Interpretation of Type 2 Diabetes and Related Disorders by Milind Watve investigates diabetes from an evolutionary perspective, suggesting...
Adventures on the Alimentary Canal
I write about a lot of depressing subjects, and sometimes a change of pace is welcome. Mary Roach, billed as “America’s funniest science writer,” has followed up on her earlier explorations of cadavers (Stiff), sex (Bonk), the afterlife (Spook), and survival on spaceships (Packing for Mars) with a new book entitled Gulp: Adventures on the Alimentary Canal. Forget all that mythology about...
Comprehending the Incomprehensible
Medicine is impossible. Really. The amount of information that flows out the interwebs is amazing and the time to absorb it is comparatively tiny. If you work, sleep and have a family, once those responsibilities are complete there is remarkably little time to keep up with the primary literature. I have made two of my hobbies (blogging and podcasting) dovetail with my...
Epigenetics: It doesn’t mean what quacks think it means
Epigenetics. You keep using that word. I do not think it means what you think it means. I realize I overuse that little joke, but I can’t help but think that virtually every time I see advocates of so-called “complementary and alternative medicine” (CAM) or, as it’s known more commonly now, “integrative medicine” discussing epigenetics. All you have to do to view...
Closing out 2012 with a bit of fun: Do you want some quantum with that pseudoscience?
today is the last day of 2012. As I contemplated what I’d write for my last post of 2012, I wondered what to do. Should I do a “year in review” sort of post? Naahh. Too trite and too much work. Should I just do what I normally do? There are, after all, many topics that are out there, some of them...