Tag: Bayesian analysis
Aromatase inhibitors and acupuncture in breast cancer: Spinning a negative study, four years later
Four years ago, I wrote about an essentially negative study looking at whether acupuncture could alleviate joint pain caused by aromatase inhibitors, a common treatment for estrogen-sensitive breast cancer. The study's back, and it doesn't look any more positive.
Acupuncture versus breast cancer treatment-induced joint pain: Spinning another essentially negative study
The investigators behind a recent clinical trial testing acupuncture to treat joint pain caused by aromatase inhibitors used to treat breast cancer are spinning it as a positive study. As is usually the case for acupuncture studies. It isn't
P Value Under Fire
The greatest strength of science is that it is self-critical. Scientists are not only critical of specific claims and the evidence for those claims, but they are critical of the process of science itself. That criticism is constructive – it is designed to make the process better, more efficient, and more reliable. One aspect of the process of science that has received...
Psychology Journal Bans Significance Testing
This is perhaps the first real crack in the wall for the almost-universal use of the null hypothesis significance testing procedure (NHSTP). The journal, Basic and Applied Social Psychology (BASP), has banned the use of NHSTP and related statistical procedures from their journal. They previously had stated that use of these statistical methods was no longer required but can be optional included....
Beware The P-Value
The p-value was meant to be used as a convenient and quick test to evaluate how likely a result was due to chance, or a real effect. It has since come to be treated as an indication of importance or truth, particularly in the CAM world. This is a problem.
Of the Trial to Assess Chelation Therapy, Bayes, the NIH, and Human Studies Ethics
An experiment is ethical or not at its inception; it does not become ethical post hoc—ends do not justify means. ~ Henry K. Beecher A couple of weeks ago, Dr. Josephine Briggs, the Director of the National Center for Complementary and Alternative Medicine (NCCAM), posted a short essay on the NCCAM Research Blog touting the results of the Trial to Assess Chelation...
5 out of 4 Americans Do Not Understand Statistics
Ed: Doctors say he’s got a 50/50 chance at living. Frank: Well there’s only a 10% chance of that Naked Gun There are several motivations for choosing a topic about which to write. One is to educate others about a topic about which I am expert. Another motivation is amusement; some posts I write solely for the glee I experience in deconstructing...
A Skeptical Look at Screening Tests
Not all screening tests are worth taking. And in particular, some screening tests are worthless.
“Moneyball,” the 2012 election, and science- and evidence-based medicine
Regular readers of my other blog probably know that I’m into more than just science, skepticism, and promoting science-based medicine (SBM). I’m also into science fiction, computers, and baseball, not to mention politics (at least more than average). That’s why our recent election, coming as it did hot on the heels of the World Series in which my beloved Detroit Tigers utterly...
The Power of Replication – Bems Psi Research
I love reading quotes by the likes of Karl Popper in the scientific literature. A recent replication of Bem’s infamous psi research, Feeling the Future, gives us this quote: Popper (1959/2002) defined a scientifically true effect as that “which can be regularly reproduced by anyone who carries out the appropriate experiment in the way prescribed.” The paper is the latest replication of Daryl Bem’s...