Results for: abstract
The Science of Clinical Trials
Science-based medicine is partly an exercise in detailed navel gazing – we are examining the use of science in the practice of medicine. As we use scientific evidence to determine which treatments work, we also have to examine the relationship between science and practice, and the strengths and weaknesses of the current methods for funding, conducting, reviewing, publishing, and implementing scientific research...
Cranial Manipulation and Tooth Fairy Science
Tooth Fairy Science is science that studies a phenomenon that doesn’t exist. You can do studies on the Tooth Fairy; for instance, comparing how much money she leaves to kids in different socioeconomic groups. You can do studies on the memory of homeopathic water. You can do studies on the therapeutic effects of smoothing out wrinkles in the imaginary human energy field...
Survey Says… Infectious Disease Docs and CAM
Surveys are evidently a popular way to get a paper published. Put “complementary alternative medicine survey” into Pubmed and get 2,353 hits. I would have trouble coming up with a hundred groups about whom I would be interested in their use of SCAMs, but I tend to be a lumper rather than a splitter. But if you want to know about SCAM...
E-cigarettes: The growing popularity of an unregulated drug delivery device
This post is not about vaccines (for a change). However, I deem it appropriate to mention that one of the topics that I blog most frequently about is vaccines and how the antivaccine movement pushes pseudoscience and quackery based on its apparently implacable hatred of vaccines. (You’ll see why very shortly.) It seems almost as long as my interest in the topic...
Autism and Induced Labor
A recently published epidemiological study in JAMA Pediatrics looked at the association between induction and enhancement of labor and the risk of autism. The researchers found a positive association, especially with males. The study has been variously reported in the popular press with causal interpretations not justified by the data. The study itself is very robust – the authors looked at 625,042...
A Different Perspective: Placebo, SCAM, and Advertising
Summertime, time, time Child, the living’s easy. Fish are jumping out And the handicap, Lord Handicaps high, Lord so high ~ Janis Joplin It is summer. Time for the kids and the outside, not the computer. What follows is a summertime blog entry, for which I admit to feeling guilty for the comparatively little time I have spent on it, but as...
“Postnatal depression blood test breakthrough” or Churnalism?
“Postnatal depression blood test breakthrough” proclaimed the headline. The UK Guardian article then declared: British doctors reveal ‘extremely important’ research that could help tens of thousands of women at risk. Here it comes. Readers were going to be fed a press release generated by the study’s authors and forwarded undigested by the media but disguised as writings of a journalist. If only...
The Overuse of Antibiotics for Viral Infections in Children
“For every complex problem there is an answer that is clear, simple, and wrong.” -H. L. Mencken As I sit in an apartment full of unpacked boxes and grumpy children, only a few days removed from driving 1,600 miles to a 3rd floor walk-up and a better life just outside of Boston, I find the task of writing a post somewhat daunting....
The difference between science-based medicine and CAM
There is a huge difference between science-based medicine (SBM) and so-called "complementary and alternative medicine" (CAM) or, as it's increasingly called, "integrative medicine." That difference is that SBM changes with new science. The change might be messier and slower than we would like, but eventually science and evidence win out.
A Skeptical Look at Screening Tests
Not all screening tests are worth taking. And in particular, some screening tests are worthless.