Off-Label Use of Prescription Drugs
A recent survey of 599 primary care physicians and 600 psychiatrists found that: The adjusted response rate was 47%, respondents were similar to non-respondents, and physicians commonly prescribed the drugs examined. The average respondent accurately identified the FDA-approval status of just over half of the drug-indication pairs queried (mean 55%; median 57%). Accuracy increased modestly (mean 60%, median 63%) when limited to...
James Reston’s Tooth of Gold
One of the fathers of critical thinking and skeptical inquiry, the French philosopher Bernard le Bovier de Fontenelle (1657–1757) recounts in 1687 in his Histoire des oracles–a debunking book on popular beliefs, myths and superstitions that caused tremendous stir in theological and philosophical circles of his time–a colorful story that could very well illustrate the flurry of interest and research in acupuncture...
The perils and pitfalls of doing a “vaccinated versus unvaccinated” study
The anti-vaccine movement is nothing if not plastic. It “evolves” very rapidly in response to selective pressures applied to it in the form of science refuting its key beliefs. For instance, when multiple studies looking at the MMR vaccine and autism failed to confirm the myth that the MMR causes autism or “autistic enterocolitis,” most recently late last year, it was not...
Science versus pseudoscience
I know this one’s been floating around the blogosphere for a while, but it finally made its way to me at a time when I needed something lighthearted and amusing (warning: some profanity and at least one use of the “F” word): Best quotes: “Well, science doesn’t know everything.” Well, science knows it doesn’t know anything, otherwise it would stop … But...
Functional Medicine IV
When I started this series on Functional Medicine, David Gorski suggested looking at Mark Hyman’s web page, which I had seen months before, but thought did not reveal much. That was a wrong. It shows a lot, and I suggest bloggers et al review it. So I decided on a fourth “functional medicine” (FM) installment, in search of what it FM really...
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August 22, 2009
A Defense of Childhood Influenza Vaccination and Squalene-Containing Adjuvants; Joseph Mercola’s “Dirty Little Secret”
Fall is around the corner, and with it comes the influenza season. Each year an average of 200,000 people in the US are hospitalized with influenza, and 36,000 die.1,2 With the addition of the novel H1N1 strain (swine flu), this season promises to be more interesting, and even less predictable, than most. There can be no doubt, however, that this one set of...
WooMD
Consider this list: Sex Matters: tuning in to what turns you on. Ticker tune-up tips for guys. Manatomy explained. Burning down under? It’s time to fess up. Pumped Up: ED meds aren’t working? An implant could be the solution. When your hoo-ha’s burning, don’t use this common cure! Go Om: Meditation can be the healthy answer for type A’s. Sexy Seniors: The...
Science-Based Medicine 101: Reproducibility
So far I have explained why most research (if not carefully designed) will lead to a false positive result. This inherent bias is responsible for many of the illusionary treatment benefits that we hear about so commonly through the media (whether they’re reporting about CAM or Western medicine), because it is their job to relay information in an entertaining way more so...
New SBM Resource – and a Word on Vaccines
We frequently receive requests from readers, our colleagues in medicine or fellow science bloggers for the best reference site that has all the information they need on a specific topic. There are many excellent resources on the net, but nothing I know of that quite puts it all together in that way – one-stop shopping for up-to-date information on the topics we...