Is there a role for speculative journals like Medical Hypotheses in the scientific literature?
The core information supporting science-based medicine resides in the scientific literature. There, scientists and physicians publish the results of experiments and clinical trials that seek to understand the biological mechanisms by which the human body functions and through which disease forms and to apply this understanding to test new treatments for diease. Consequently, the quality and integrity of the biomedical literature are...
Just the Facts
Get your facts first, and then you can distort them as much as you please. —Mark Twain There is an educational approach to becoming a doctor. It involves learning massive amounts of basic science, followed by massive amounts of pathophysiology, which barely prepares you for the clinical years of the last half of medical school and subsequent residency, with the massive knowledge...
CAM on campus: Integrative Medicine
My previous posts have described guest lecturers at my medical school campus, invited by a student interest group in CAM. Those events continue; currently ongoing is an 8-weekend certification course in Ayurveda for the subsidized cost of $1500 (includes “tuition, syllabus, and personal guru”). I could pick on this student group, but what’s the point? There will always be medical students who...
Plausibility in Science-Based Medicine
A question that arises often when discussing the optimal role of science in medicine is the precise role of plausibility, or prior probability. This is, in fact, the central concept that separates (for practical if not philosophical reasons) science-based medicine (SBM) from evidence-based medicine (EBM). The concept featured prominently in the debate between myself and Dr. Katz at the recent Yale symposium...
The 2nd Yale Research Symposium on Complementary and Integrative Medicine. Part II
The Main Event: Novella vs. Katz The remainder of the Symposium comprised two panels. The first was what I had come to see: a Moderated Discussion on Evidence and Plausibility in the Context of CAM Research and Clinical Practice, featuring our Founder, Steve Novella, who is also Assistant Professor of Neurology at Yale; and David Katz, the speaker who had borne the...
Halsted: The Father of Science-Based Surgery
One (dark and stormy?) night in 1882, a critically ill 70 year old woman was at the verge of death at her daughter’s home, suffering from fever, crippling pain, nausea, and an inflamed abdominal mass. At 2 AM, a courageous surgeon put her on the kitchen table and performed the first known operation to remove gallstones. The patient recovered uneventfully. The patient...
A nutritional approach to the treatment of HIV infection—same old woo?
I get all sorts of mail. I get mail from whining Scientologists, suffering patients, angry quacks—and I get lots of promotional material. I get letters from publishers wanting me to review books, letters from pseudo-bloggers wanting me to plug their advertiblog—really, just about anything you can imagine. Most of the time I just hit “delete”; it’s obvious that they’ve never read my...
Biologie Totale and other bastard offspring of Ryke Geerd Hamer’s German New Medicine
A few months ago, I wrote about a particularly nasty form of cancer quackery known as the “German New Medicine” or Die Germanische Neue Medizin in German. As you may recall, the German New Medicine is based on the nonsensical idea that cancer arises from an internal emotional conflict. This conflict then results in what is called the “Dirk Hamer Syndrome” (DHS)...
The 2nd Yale Research Symposium on Complementary and Integrative Medicine. Part I
March 4, 2010 Today I went to the one-day, 2nd Yale Research Symposium on Complementary and Integrative Medicine. Many of you will recall that the first version of this conference occurred in April, 2008. According to Yale’s Continuing Medical Education website, the first conference “featured presentations from experts in CAM/IM from Yale and other leading medical institutions and drew national and international...
A Welcome Upgrade to a Childhood Vaccine – PCV 13
Children aren’t supposed to die. That so many of us accept this statement without a blink is remarkable and wonderful, but it is also a very recent development in human history. Modern sanitation, adequate nutrition, and vaccination have largely banished most of the leading killers of children to the history books. Just look at the current leading causes of childhood death in...