Category: Clinical Trials

Trolley_problem

Influenza Vaccine and Health Care Workers. More than one way to skin a literature

There are many ways to apply the medical literature. For me it starts with the premise that health care workers may not injure a human being or, through inaction, allow a human being to come to harm.

/ March 3, 2017
A thousand points of pseudo-medicine

Corrigendum. The Week in Review for 02/19/2017

More poorly done acupuncture studies. Burzynski eats just desserts. Italians like homeopathy. New Jersey is going after Oregon. And more

/ February 19, 2017
Tools required to examine the growing high quality chiropractic literature on efficacy.

Spinal Manipulation for Back and Neck Pain: Does It Work? Annotated.

Spinal Manipulation for Back and Neck Pain: Does It Work? You would think it does if you read the article but not if you actually read the literature.

/ February 17, 2017
A thousand points of pseudo-medicine.

Corrigendum. The week in review for 02/12/2017

The week in review. Chiropractic and stroke. Integrative Medical doctors don’t trust vaccines. Death from medical marijuana. Shilajit: compost or mulch oozing from Himalayan rocks. India goes full Tuskeegee with AIDS. And more!

/ February 12, 2017
MacularDegenerationFundus

Re-thinking Antioxidant Supplementation for Macular Degeneration

After the AREDS trial, people with moderate to severe age-related macular degeneration were advised to take dietary supplements to slow the progression of the disease. But some experts say the trial actually showed supplements don't work, and might even make some patients worse.

/ February 7, 2017
Translational research and preclinical data

Donald Trump versus the FDA: Is the standard of evidence for drug approval actually too low rather than too high?

All of the candidates being considered by President Trump for FDA Commissioner believe that the FDA is too strict in its standards for approving new drugs. In a commentary in Nature last week, two bioethicists argued that, at least in terms of preclinical data, the standard of evidence is actually too low. Which is correct?

/ February 6, 2017
A_galactic_maelstrom duty calls

Corrigendum. The week in SBM for 1.22.2017

Not every article and study that pops up my feeds in the world of pseudo-medicine is worthy of a complete blog post. But they need to be noticed and commented upon: Liver toxicity from herbs. Popped lungs from acupuncture. Chiropractic does not help scoliosis. Yoga is just exercise. There are eight kinds of wind: Great Feathery Wind, Scheming Wind, Hard Wind, Great...

/ January 22, 2017
Not even the Bocca della Verità can tell if a Chinese medical study is fabricated.

Chinese BioMedical Research: Sturgeon’s Law In Action

A Chinese government investigation has found that 80%, yes eighty percent, of Chinese biomedical research is fabricated. I bet that is an underestimate for Traditional Chinese Pseudo-Medicine.

/ January 20, 2017
nof1book2c

Myths integrative medicine sells us: “We never advocate alternative medicine without conventional medicine”

"Integrative medicine" (IM) effectively integrates quackery with real medicine. The main talking point by advocates of IM meant to deflect this criticism is that IM practitioners always use alternative medicine with conventional medicine and never advocate the use of alternative medicine alone. A new book by a prominent advocate of IM suggests that this talking point is at best self-delusion among academics...

/ January 8, 2017
scatter-of-acupuncture-needles

Acupuncture’s Big Myth

The great acupuncture myth? No spoilers from me. Read the entry or skip to the penultimate paragraph to find out.

/ January 6, 2017