Category: Clinical Trials
The Stem Cell Ophthalmology Treatment Study
In this study we have 300 patients with 47 different diseases subject to 7 experimental treatments among 3 treatment groups and no control group. What could possibly go right?
Poor Science Reporting and Premature Enthusiasm
Press releases often outpace the data. Here are some examples of over-enthusiastic reporting on extremely preliminary research.
The misuse and abuse of meta-analyses
The meta-analysis has been misused and weaponized to promote dubious COVID-19 treatments.
Virtual Reality Therapy
Are virtual reality headsets a valid tool for treating back pain? Maybe.
Pfizer’s new COVID-19 protease inhibitor drug is not just “repackaged ivermectin”
Pfizer recently announced that its new protease inhibitor-based drug was 89% effective in preventing hospitalization due to COVID-19 and it is seeking an emergency use authorization for it from the FDA. Antivaxxers claim that ivermectin targets the same protease and is being "suppressed" to protect Pfizer's profits from the new drug. What's the real story? Hint: Antivaxxers took a grain of truth...
What the heck happened to The BMJ?
Last week, The BMJ published an "exposé" by Paul Thacker alleging patient unblinding, data falsification, and other wrongdoing by a company running three sites for the massive clinical trial of the Pfizer COVID-19 vaccine. It was a highly biased story embraced by antivaxxers, with a deceptively framed narrative and claims not placed into proper context, leading me to look into the broader...
Laser Therapy for Vaginal Rejuvenation
Some doctors are offering laser therapy for "vaginal rejuvenation". It is no more effective than placebo, can cause harm, and is very expensive.
Ivermectin is the new hydroxychloroquine, take 6: Incompetence and fraud everywhere!
Ivermectin is the new hydroxychloroquine, a drug repurposed for COVID-19 that almost certainly doesn't work but is still being touted as a "miracle cure" by quacks, grifters, and political ideologues. Are the data supporting it all fraud?
Preventing Malaria: A Glimmer of Hope?
A recent clinical trial tested a new approach to malaria prevention involving monoclonal antibodies.
Ivermectin is the new hydroxychloroquine, take 5: The Nobel Prize gambit
Ivermectin continues to be the new hydroxychloroquine, an unproven repurposed drug promoted to treat COVID-19. Now the advocates are pointing to the history of the drug's developers being awarded the Nobel Prize in Medicine, as though that has anything to do with its effectiveness against COVID-19.