Category: Clinical Trials

TIC’D OFF

Two years ago we discussed the TicTocStop, a dental appliance that the inventors assured us would help mitigate the symptoms of Tourette Syndrome. In the intervening years things have...not gone well. This illustrates the need for skepticism regarding questionable medical claims, and the importance of initiatives like AllTrials to ensure the good, the bad, and the ugly research is available to everyone.

/ May 4, 2018

Stem Cell Tourism Comes Home

You used to have to go to China to get ripped off by fraudulent stem cell clinics. Now you can get conned right here at home.

/ May 2, 2018

Bee Venom is Snake Oil

Bee venom acupuncture is a double-barrel pseudoscience that provides new example of an old problem - the use of poor quality preclinical research to justify the inclusion of nonsense in medicine.

/ April 25, 2018

Dog breath and stinky studies: Do pets need to be knocked out for dental care?

Most professional veterinary organizations recommend anesthesia to ensure thorough dental care for pet dogs and cats. Despite this, some companies are trying to mislead the pet-owning public by claiming they have high quality evidence showing they provide the same benefit without the risks. Their research smells worse than old chihuahua breath.

/ April 13, 2018

PSA Screening for Prostate Cancer

PSA testing is controversial. A new study finds that PSA screening for prostate cancer offers no survival benefits.

/ March 22, 2018

The Debate Is Over: Antidepressants DO Work Better Than Placebo

The idea that antidepressants are no more effective than placebo has been put to rest. They clearly work when used appropriately, although the effect size is not as large as the published studies have suggested.

/ March 6, 2018

Where Are We With the Replication “Crisis”

The replication problem is not as bad as the sensational reporting has suggested. But it is still a legitimate issue that needs to be addressed. 

/ February 28, 2018

The final push to pass a federal version of the cruel sham of “right-to-try” is under way

Right-to-try laws are a cruel sham that claim to help terminally ill patients by providing them with earlier access to experimental therapeutics, even though they do very little in this regard. Promoted primarily by the libertarian think tank the Goldwater Institute, in reality they are a strategy to weaken the FDA's regulatory power to assure that marketed drugs are safe and effective....

/ January 15, 2018

A Misguided Study to Test the Reliability of Traditional Chinese Medicine Pulse Diagnosis

Pulse diagnosis and tongue diagnosis are widely used in traditional Chinese medicine. They are based on imagination, not on anatomical and physiologic reality.

/ December 26, 2017

I Was Wrong about Protandim

A seriously flawed Protandim study seemed to show that side effects were no more common than with placebo. Actually, they were almost twice as common. The researchers were looking at the wrong numbers and didn't even add correctly.

/ December 5, 2017