Dexamethasone and Hydroxychloroquine: Why Randomized Controlled Trials Matter
What does the best evidence tell us about hydroxychloroquine and dexamethasone?
Hydroxychloroquine to treat COVID-19: Evidence can’t seem to kill it
Despite the accumulating negative evidence showing that hydroxychloroquine doesn't work against COVID-19, activists continue to promote it as a way out of the pandemic. This week, the AAPS and a Yale epidemiologist joined the fray with embarrassingly bad arguments.
An incomplete list of COVID-19 quackery
Possibly the only thing spreading faster than COVID-19 is the pseudoscience about COVID-19.
COVID-19: Out-of-control science and bypassing science-based medicine
During the COVID-19 pandemic, there hasn't just been a pandemic of coronavirus-caused disease. There's also a pandemic of misinformation and bad science. It turns out that doctors today are just as prone as doctors 100 years ago during the 1918-19 influenza pandemic to bypass science-based medicine in their desperation to treat patients.
Hydroxychloroquine, retinal toxicity, and COVID-19
Hydroxychloroquine is being promoted as a treatment or prevention for COVID-19 based on questionable evidence. The long-term impact of hydroxychloroquine on the retina introduces another reason to be cautious about its use outside of clinical trials.
Hydroxychloroquine and the price of abandoning of science- and evidence-based medicine
Based on anecdotal evidence early in the pandemic and then-unreported clinical trials, followed by hype and bad studies by French "brave maverick doctor" Didier Raoult, antimalarial drugs hydroxychloroquine and chloroquine became the de facto standard of care for COVID-19, despite no rigorous evidence that they worked. A steady drip-drip-drip of negative studies has led doctors and health authorities to rethink and backtrack,...
“Miracle cure” testimonials aside, azithromycin and hydroxychloroquine probably do not work against COVID-19
Here we go again. Didier Raoult has published another uninformative study looking at the use of hydroxychloroquine and azithromycin to treat COVID-19. Unfortunately, recent data examining these drugs have been trending in the direction of the conclusion that these drugs probably don't work against COVID-19 but do cause harm. Sadly, the lack of evidence hasn't stopped the hucksters from promoting hydroxychloroquine as...
TCM for COVID-19
Despite the many claims, there is no real evidence that traditional Chinese medicine (TCM) is effective for prevention or treatment of COVID-19
Hydroxychloroquine and azithromycin versus COVID-19: Grift, conspiracy theories, and another bad study by Didier Raoult
On Friday, Prof. Didier Raoult posted another study of azithromycin and hydroxychloroquine used against COVID-19. It is a single arm observational study of patients with mostly mild (or even asymptomatic) disease that is painfully uninformative with respect to the question of this treatment's effectiveness. That didn't stop America's Quack Dr. Oz and other grifters from touting Raoult's study, as well as a...
Are hydroxychloroquine and azithromycin an effective treatment for COVID-19?
Saturday morning, President Trump Tweeted a claim that the combination of azithromycin and hydroxychloroquine "have a real chance to be one of the biggest game changers in the history of medicine" and hoped that they be "put in use IMMEDIATELY" to treat COVID-19. His claims were based on a single clinical trial out of France. Unfortunately, although it is not implausible that...