Tag: animal models
One reason mouse studies often don’t translate to humans very well
Mouse models are often used as preclinical models of human disease, but the number of drugs that succeed in mice but go on to be approved as a drug for humans is only about one in ten. A new study comparing gene expression in the cells of human brains with those of mouse brains provides new insight into why.
Drug maker challenges FDA on animal testing
A drug maker claims an FDA-required toxicity study in animals is unnecessary to determine safety and urges others to question the routine use of animal testing.
The Seralini GMO Study – Retraction and Response to Critics
Elsevier has announced that they are retracting the infamous Seralini study which claimed to show that GMO corn causes cancer in laboratory rats. The retraction comes one year after the paper was published, and seems to be a response to the avalanche of criticism the study has faced. This retraction is to the anti-GMO world what the retraction of the infamous Wakefield...
Mouse Model of Sepsis Challenged
A recent study published in the Proceedings of the National Academy of Sciences calls into question the standard mouse model of sepsis, trauma, and infection. The research is an excellent example of how proper science investigates its own methods. Mouse and other animal models are essential to biomedical research. The goal is to find a specific animal model of a human disease...