Category: Pharmaceuticals

Weak drug regulation and patient tragedies: We’ve seen this story before

Plenty of new drugs, but few that are truly innovative. Growing costs from their use. Physicians deemed “Dupes of Big Pharma” for their interactions with the pharmaceutical industry. A call to produce better information on which drugs work best. Finally, shoddy drug manufacturing is injuring and even killing patients. These stories could be lifted from today’s headlines — but they’re actually from...

/ October 25, 2012

News flash! Doctors aren’t all compliant pharma drones!

There’s an oft-quoted saying that’s become a bit of a cliché among skeptics that goes something like this: There are two kinds of medicine: medicine that’s been proven scientifically to work, and medicine that hasn’t. This is then often followed up with a rhetorical question and its answer: What do call “alternative medicine” that’s been proven to work? Medicine. Of course, being...

/ September 24, 2012

The HCG Diet: Yet another ineffective quick fix diet plan and supplement

I contribute biweekly to Science-Based Medicine and could easily devote every post to writing about weight loss supplements, and never run out of topics. As soon as one quick fix falls out of favour, another inevitably replaces it. Some wax and wane in popularity. And pharmacies don’t help the situation. I cringe every time I walk down the aisle where weight loss...

/ July 19, 2012

Science, Evidence and Guidelines

Disclaimer:  I am a paid Medscape  blogger and writer, and since they are in part supported by advertisements from the Pharmaceutical companies,  indirectly I am in the thrall of Big Pharma. I found Harriet’s post on the Medscape Connect topic of How do you feel about Evidence-Based Medicine? interesting. I wondered about the breakdown of the comments by both specialty and opinions...

/ June 15, 2012

How do we avoid harming the elderly with prescription drugs?

Is the best medicine no medicine at all? Sometimes. My past posts have emphasized that the appropriateness of any drug depends on an evaluation of benefits and risks. There are no completely safe interventions, and no drug is free of any side effects. Our choice is ideally informed by high-quality data like randomized controlled trials, with lots of real-world experience so we...

/ June 7, 2012

Choosing Wisely: Five things Pharmacists and Patients Should Question

Is the health care spending tide turning? Unnecessary medical investigations and overtreatment seems to have entered the public consciousness to an extent I can’t recall in the past. More and more, the merits of medical investigations such as mammograms and just this week, PSA tests are being being widely questioned. It’s about time. Previous attempts to critically appraise overall benefits and consequences...

/ May 24, 2012
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Cannibalism?

For all the goofiness that is SCAM, I never thought I would have a post with Cannibalism in the title. The ability for humans to find imaginary healing properties in everything from duck liver and heart diluted 1:100 200 times, rhinoceros horns, and waving hands over people to adjust energy fields that do not exist is remarkable. Somehow I never thought Jeffrey...

/ May 18, 2012

The drug expiry date: A necessary safety measure, or yet another Big Pharma conspiracy?

Consider this scenario: You’re in good health and take no prescription drugs. You use the following remedies occasionally: Excedrin for the rare migraine Arnica 30CH for bumps and bruises Echinacea capsules, when you feel a cold coming on Today you look in your cupboard, and notice all three products expired last year. Would you still consider taking any of them? Why or...

/ May 10, 2012

Gold mine or dumpster dive? A closer look at adverse event reports

All informed health decisions are based on an evaluation of expected risks and known benefits. Nothing is without risk. Drugs can provide an enormous benefit, but they all have the potential to harm. Whether it’s to guide therapy choices or to ensure patients are aware of the risks of their prescription drugs, I spend a lot of time discussing the potential negative consequences of...

/ April 26, 2012

Feet of Clay

It has been tough in Portland this year. The Trailblazers, our NBA, and only professional team, started out on a tear, then went right down the toilet. It is painful to see such promise dribbled away. Sigh. Why is elation always followed by disappointment? Everyone and everything has feet of clay. Except Cassius Marcellus. At the beginning of March the NEJM had...

/ March 31, 2012