All posts by Steven Novella

Founder and currently Executive Editor of Science-Based Medicine Steven Novella, MD is an academic clinical neurologist at the Yale University School of Medicine. He is also the host and producer of the popular weekly science podcast, The Skeptics’ Guide to the Universe, and the author of the NeuroLogicaBlog, a daily blog that covers news and issues in neuroscience, but also general science, scientific skepticism, philosophy of science, critical thinking, and the intersection of science with the media and society. Dr. Novella also has produced two courses with The Great Courses, and published a book on critical thinking - also called The Skeptics Guide to the Universe.

Author

  • Founder and currently Executive Editor of Science-Based Medicine Steven Novella, MD is an academic clinical neurologist at the Yale University School of Medicine. He is also the host and producer of the popular weekly science podcast, The Skeptics’ Guide to the Universe, and the author of the NeuroLogicaBlog, a daily blog that covers news and issues in neuroscience, but also general science, scientific skepticism, philosophy of science, critical thinking, and the intersection of science with the media and society. Dr. Novella also has produced two courses with The Great Courses, and published a book on critical thinking - also called The Skeptics Guide to the Universe.

The front view of the United States Supreme Court building in Washington, D.C., featuring tall columns, statues, steps leading to the entrance, and a clear blue sky overhead.

Is (Conversion) Therapy Speech?

The US Supreme Court recently heard a case that could have devastating effects on the standard of care in medicine, and the indicators of where the justices fall are not good. The case is Chiles v Salazar, in which a licensed therapist is arguing that a Colorado law banning conversion therapy for gay and trans clients violates her free speech. So the...

/ October 15, 2025
Diagram shows groups of cells labeled T, separated into CD4+ and CD4+CD25+ categories, with arrows indicating that CD4+ cells lead to a sick mouse, while CD4+CD25+ cells with CD4+ cells lead to a healthy mouse.

Nobel Prize in Medicine: Peripheral Immune Tolerance

Each year I like to write a post about the Nobel Prize in Physiology or Medicine. While advocating for higher standards of science in medicine we tend to spend much of our time criticizing pseudoscience, so I like to balance that by occasionally just celebrating great medical science, and the Nobel Prize is a great opportunity. The 2025 award for physiology or...

/ October 8, 2025

The Cholesterol Wars Continue

As a first approximation it seems that the purpose of social media is to misrepresent medical information and to promote wellness gurus who basically have no idea what they are talking about. Part of the problem is that medical science is often complex, and the short attention-span format of social media often favors simple clean narratives. So “wellness influencers” dominate while genuine...

/ October 1, 2025
Former President Donald Trump speaks at a podium with officials standing behind him during a televised press conference. News ticker mentions a potential Tylenol-autism link and displays the time as 2:49 PM.

That Trump, RFK, Oz Presser

Yes, we have to talk about that press conference with Trump, RFK Jr and Dr. Oz., which some are characterizing as the absolutely worst firehose of medical misinformation coming from the White House in American history. I think that is fair. This was the presser we knew was coming, and many of us were dreading. It was worse than I anticipated. I wrote a...

/ September 24, 2025
A stained cross-section of a brain shows labeled anatomical regions, including "CX" and "CC," with dark and light regions indicating different tissue densities. A scale bar at the bottom right reads 0.5 mm.

Stem Cell Stroke Therapy

We have written quite a bit about fraudulent stem cell clinics. They have followed a typical pattern of overhyping new potential therapies, with some clinics going as far as selling fake stem cell treatments. Stem cells were a likely target – they sound extremely advanced, their potential is easy to understand, and you can use them to justify extreme claims of healing....

/ September 17, 2025
An open box of acetaminophen 500 mg tablets with two blister packs, each containing white oval pills. The box is labeled "24 tablets / oral use" and "extra strength" on a light blue background.

Tylenol and Autism

Earlier this year, HHS secretary RFK Jr. predicted that, “By September, we will know what has caused the autism epidemic and we’ll be able to eliminate those exposures.” Scientists have been researching autism for decades, including what factors are driving changes in diagnostic patterns. Promising such a major breakthrough in just six months is beyond ridiculous, and strongly implies that RFK Jr....

/ September 10, 2025
Illustration of a shark behind a laptop displaying a bar chart, a clipboard with a medical symbol, a pill bottle, and scattered pills, symbolizing threats or dangers in healthcare or medicine.

The Problem with Predatory Journals

The World Wide Web has proven to be a transformative communication technology (we are using it right now). At the same time there have been some rather negative unforeseen consequences. Significantly lowering the threshold for establishing a communications outlet has democratized content creation and allows users unprecedented access to information from around the world. But it has also lowered the threshold for...

/ September 3, 2025
Two surgeons in blue scrubs and masks perform a surgical procedure, focusing intently on the operation site, with medical instruments and equipment visible on the table.

First Pig Lung to Human Transplant

In the midst of all the controversy surrounding the science of healthcare, certain technologies continue to progress in the background, with the promise of transforming the practice of medicine. One of them is the development of genetically modified animals as a source for organ transplants. I most recently wrote about this earlier this year, specifically about an experiment to transplant a pig...

/ August 27, 2025
Christian Elliot and viral disinformation

Health Narratives on Social Media

Engaging on social media about health issues can be daunting. I know this is not news, but it is important to understand what is happening phenomenologically. I also think it’s a microcosm of what’s happening to our society in general because of social media – we no longer have a shared fact-based reality as people increasingly live in different universes of information....

/ August 20, 2025

Lithium and Alzheimer’s Disease

This is an interesting story, which has been all over the news so worthy of covering here. Alzheimer’s disease (AD), the major cause of dementia in humans, is a very complex disease. We have been studying it for decades, revealing numerous clues as to what kicks it off, what causes it to progress, and how to potentially treat it. This has lead...

/ August 13, 2025