Tag: Dementia

A human brain showing fronto-temporal lobe degeneration, often associated with dementia

Declining Dementia

Dementia is a significant health burden of increasing significance as our population ages. Worldwide the prevalence of dementia is 5-7% in people 60 years and older, with risk doubling every 5 years after age 60. About 5.4 million Americans are living with dementia. Dementia is a general category referring to a chronic decline in overall cognitive function. The most common cause of...

/ November 23, 2016

Exercise and Memory

There is no escaping the evidence that regular moderate exercise is associated with a host of medical benefits. Among those benefits are perhaps improved memory and cognition, and questionably a decreased risk of developing dementia. The latest study to show this correlation involved younger and older adults who wore a step-monitor. The number of steps they took during the study interval was...

/ November 25, 2015

Don’t Believe The Hype: Cholinesterase Inhibitors As A Treatment For Dementia

I distinctly remember the day I attended a “drug lunch” (as a PM&R resident in New York City) to learn about the value of donepezil (Aricept) for the treatment of dementia. I was astonished by the drug’s lack of efficacy – the graph displayed in the PowerPoint show demonstrated a 2-point improvement on the Mini Mental State Exam (MMSE), an effect that...

/ January 21, 2010