Tag: Cochrane Collaboration
The strange saga of Peter Gøtzsche and Physicians for Informed Consent
Recently, it was noted that Peter Gøtzsche, formerly of Cochrane Nordic, was featured on the speaker list for an antivaccine quackfest organized by the antivaccine group Physicians for Informed Consent, along with Robert F. Kennedy, Jr., Toni Bark, and Marry Holland. Two days later, he announced that he would not be speaking there. So what happened? And what is Physicians for Informed...
New evidence, same conclusion: Tamiflu only modestly useful for influenza
Does Tamiflu have any meaningful effects on the prevention or treatment of influenza? Considering the drug’s been on the market for almost 15 years, and is widely used, you should expect this question has been answered after 15 flu seasons. Answering this question from a science-based perspective requires three steps: Consider prior probability, be systematic in the approach, and get all the...
Cochrane is Starting to ‘Get’ SBM!
This essay is the latest in the series indexed at the bottom.* It follows several (nos. 10-14) that responded to a critique by statistician Stephen Simon, who had taken issue with our asserting an important distinction between Science-Based Medicine (SBM) and Evidence-Based Medicine (EBM). (Dr. Gorski also posted a response to Dr. Simon’s critique). A quick-if-incomplete Review can be found here. One...
Of SBM and EBM Redux. Part IV, Continued: More Cochrane and a little Bayes
OK, I admit that I pulled a fast one. I never finished the last post as promised, so here it is. Cochrane Continued In the last post I alluded to the 2006 Cochrane Laetrile review, the conclusion of which was: This systematic review has clearly identified the need for randomised or controlled clinical trials assessing the effectiveness of Laetrile or amygdalin for...
Of SBM and EBM Redux. Part IV: More Cochrane and a little Bayes
NB: This is a partial posting; I was up all night ‘on-call’ and too tired to continue. I’ll post the rest of the essay later… Review This is the fourth and final part of a series-within-a-series* inspired by statistician Steve Simon. Professor Simon had challenged the view, held by several bloggers here at SBM, that Evidence-Based Medicine (EBM) has been mostly inadequate...
Of SBM and EBM Redux. Part II: Is it a Good Idea to test Highly Implausible Health Claims?
Review This is the second post in a series* prompted by an essay by statistician Stephen Simon, who argued that Evidence-Based Medicine (EBM) is not lacking in the ways that we at Science-Based Medicine have argued. David Gorski responded here, and Prof. Simon responded to Dr. Gorski here. Between that response and the comments following Dr. Gorski’s post it became clear to...