Category: Pharmaceuticals

FDA warns companies selling illegal hangover remedies
The FDA recently warned seven companies not to claim that their dietary supplements can prevent, treat, or cure a hangover, because only FDA-approved drugs can make such claims. The agency also warned that NAC, a popular supplement ingredient, cannot legally be used in dietary supplements.

The TikTok “Benadryl Challenge” is demonstrating how toxic Benadryl can be
Even without the risk of overdose, there are good reasons to avoid Benadryl entirely.

Dexamethasone and Hydroxychloroquine: Why Randomized Controlled Trials Matter
What does the best evidence tell us about hydroxychloroquine and dexamethasone?

Shooting the Messenger: Activists Persecute Scientists Whose Findings They Don’t Like
Alice Dreger's book recounts many instances of shooting the messenger, when scientists were persecuted for research findings that activists found objectionable. Social justice matters, but it should rely on science and reality, not ideology.

Expert review warns against compounded bioidentical hormone therapies
A National Academies report finds widely-marketed compounded hormone replacement therapies lack evidence of safety and effectiveness, and recommends restriction of their use.

Probiotics, revisited
New guidelines do not recommend probiotics for most gastrointestinal conditions.

New Drugs for Sickle Cell Disease: Small Benefit, Large Price
The FDA has approved two new drugs to treat sickle cell disease. They don’t do much, and they are prohibitively expensive.

No, Everything You Thought You Knew About Disease Is Not Wrong
The authors of this book are not doctors or scientists, but they try to convince readers that science-based medicine gets it all wrong, that germs don't cause disease, and that drugs and vaccines can't possibly work. No, the book gets it all wrong.

COVID-19: Out-of-control science and bypassing science-based medicine
During the COVID-19 pandemic, there hasn't just been a pandemic of coronavirus-caused disease. There's also a pandemic of misinformation and bad science. It turns out that doctors today are just as prone as doctors 100 years ago during the 1918-19 influenza pandemic to bypass science-based medicine in their desperation to treat patients.

Hydroxychloroquine and the price of abandoning of science- and evidence-based medicine
Based on anecdotal evidence early in the pandemic and then-unreported clinical trials, followed by hype and bad studies by French "brave maverick doctor" Didier Raoult, antimalarial drugs hydroxychloroquine and chloroquine became the de facto standard of care for COVID-19, despite no rigorous evidence that they worked. A steady drip-drip-drip of negative studies has led doctors and health authorities to rethink and backtrack,...