Category: Epidemiology
Vaccines and infant mortality rates: A false relationship promoted by the anti-vaccine movement
The anti-vaccine movement is a frequent topic on the Science-Based Medicine blog. There are a number of reasons for this, not the least of which being that the anti-vaccine movement is one of the most dangerous forms of pseudoscience, a form of quackery that, unlike most forms of quackery, endangers those who do not partake of it by breaking down herd immunity...
The benefits and risks of folic acid supplementation
Could a vitamin with proven benefits in one group cause harm to another? That’s the growing concern with folic acid, the vitamin that dramatically reduces the risk of neural tube birth defects such a spina bifida. Studies designed to explore the possible benefits of folic acid for heart disease, stroke and cancer are giving out some worrying signs: At best, folic acid...
Deadly Indeed
There are sources of information I inclined to accept with minimal questioning. I do not have time to examine everything in excruciating detail, and like most people, use intellectual short cuts to get through the day. If it comes from Clinical Infectious Diseases or the NEJM, I am inclined to accept the conclusions without a great deal of analysis, especially for non-infectious...
Critique of “Risk of Brain Tumors from Wireless Phone Use”
Following my recent critique here of the book Disconnect by Devra Davis, about the purported dangers of cell phones to health, David Gorski asked me to comment on a recently published “review article” on the same subject. The article is entitled “Risk of Brain Tumors from Wireless Phone Use” by Dubey et al [1] published in the J. Comput Assist Tomography. At...
Breast implants and anaplastic large cell lymphoma (ALCL): Is there a link?
I must admit that I have a bit of a love-hate relationship with breast implants. On the one hand, as a breast cancer surgeon, I see them as a major benefit to my patients who are unfortunate enough to require mastectomy in order to control their disease. The armamentarium of techniques for reconstructing breasts after mastectomy generally falls into one of two...
Statins – The Cochrane Review
A recent Cochrane review of the use of cholesterol-lowering statin drugs in primary prevention has sparked some controversy. The controversy is not so much over what the data says, but in what conclusions to draw from the data. Statin drugs have been surrounded by controversy for a number of reasons. On the one hand they demonstrably lower cholesterol, and the evidence has...
Obesity Denial
It seems that for every established science there is an ideological group who is motivated to deny it. Denialism is a thriving pseudoscience and affects any issue with the slightest political or social implications. Sometimes, even easily verifiable facts can be denied, as people seem willing to make up their own facts as needed. Denialists have an easy job – to spread...
A Disconnect between cell phone fears and science
Disconnect: The Truth About Cell Phone Radiation, What the Industry Has Done to Hide It, and How to Protect Your Family by Devra Davis, PhD is touted as a book about the issue of cell phones and health. It is instead a tract that conspiracy theorists will love that sheds no objective light on the often confusing scientific data in this area....
CAM Use by Brain Tumor Patients
A recent article in the journal Neurology reports the results of an observational study regarding the use of so-called complementary and alternative medicine (CAM) by patients with an incurable brain glioma. They found that 40% of patients sought some type of CAM treatment. These results are in line with prior surveys, but require closer inspection. The study defined CAM as: Complementary therapy...
Freeways, autism, and correlation versus causation
I have a love-hate relationship with epidemiology. On the one hand, I love how epidemiology can look for correlations in huge sample sizes, sample sizes far larger than any that we could ever have access to in clinical trials, randomized or other. I love the ability of epidemiology to generate hypotheses that can be tested in the laboratory and then later in...