Category: Clinical Trials
What’s the harm? Stem cell tourism edition
Stem cells have become big business. Offshore clinics claim to use stem cells to treat anything from aging, diabetes, stroke, cancer, and even autism, all without compelling evidence that these treatments have any meaningful effect. Unfortunately, the potential for harm, both financial and to health, is high, as the case of Jim Gass demonstrates.
Whither the randomized controlled clinical trial?
With the rise of precision medicine and genomics, the conventional randomized clinical trial appears more and more outdated. Fortunately, clinical trials are evolving, but will it be enough to incorporate the numerous advances in "-omic" medicine in a rigorous scientific manner to benefit patients?
False balance about Stanislaw Burzynski and his disproven cancer therapy, courtesy of STAT News
One common theme that has been revisited time and time again on this blog since its very founding is the problem of how science and medicine are reported. For example, back when I first started blogging, years before I joined Science-Based Medicine in 2008, one thing that used to drive me absolutely nuts was the tendency of the press to include in...
Tai Chi versus physical therapy for osteoarthritis of the knee: How CAM “rebranding” works
“Complementary and alternative medicine” (CAM), now more frequently referred to as “integrative medicine” by its proponents, consists of a hodge-podge of largely unrelated treatments that range from seemingly reasonable (e.g., diet and exercise) to pure quackery (e.g., acupuncture, reiki and other “energy medicine”) that CAM proponents are trying furiously to “integrate” as coequals into science-based medicine. They do this because they have...
Chiropractors, Blind Pigs, and Acorns
When people are at the end of their life they like to pass on their life lessons. One thing I have never had a patient say is “Doc, I sure wish I had spent more time at work.” I try and keep that in mind, but then there are those work commitments that are hard to avoid. I need to have a...
Acupuncture does not work for menopause: A tale of two acupuncture studies
Arguably, one of the most popular forms of so-called “complementary and alternative medicine” (CAM) being “integrated” with real medicine by those who label their specialty “integrative medicine” is acupuncture. It’s particularly popular in academic medical centers as a subject of what I like to refer to as “quackademic medicine“; that is, the study of pseudoscience and quackery as though it were real...
Chiropractic- Ignoring the Precautionary Principle Since 1895
Bleh. I turned from a short trip to the city of angles with a bad man cold that just isn’t going away. Those who do primary care all tell me that whatever is going around lasts 2-3 weeks. Great. I am not sick enough to get out of work but I am not well enough to have any enthusiasm to do anything....
Statins for everyone? Not so fast.
People love the idea of preventive medicine. Preventing a disease, before it occurs, seems intuitively obvious. But when it comes to taking medicine to prevent a disease before it occurs, people tend to be much less comfortable. Not only are there the concerns about the “medicalization” of healthy people, there are good questions about benefits, risks, and costs. Cardiovascular disease will kill...
NCCIH Strategic Plan 2016-2021, or: Let’s try to do some real science for a change
It’s no secret that we at Science-Based Medicine (SBM) are not particularly fond of the National Center for Complementary and Integrative Health (NCCIH). Formerly known as the National Center for Complementary and Alternative Medicine (NCCAM) and before that the Office of Alternative Medicine, NCCIH has been the foremost government agency funding research into quackery for the last 24 years, and, of course,...
The hijacking of evidence-based medicine
A hero of the blog, John Ioannidis, worries that evidence-based medicine has been hijacked, and when Ioannidis says something we at SBM listen. But has EBM been "hijacked"?