Tag: passenger mutation
Genetics and evolution in cancer
Several new studies were published earlier this month describing the sequencing of over 2,600 cancer genomes. What the results show include what sorts of mutations drive cancer development and how evolution makes cancers so difficult to treat.
“Precision medicine”: Hope, hype, or both?
I am fortunate to have become a physician in a time of great scientific progress. Back when I was in college and medical school, the thought that we would one day be able to sequence the human genome (and now sequence hundreds of cancer genomes), to measure the expression of every gene in the genome simultaneously on a single “gene chip,” and...