Tag: donepezil

Don’t Believe The Hype: Cholinesterase Inhibitors As A Treatment For Dementia

I distinctly remember the day I attended a “drug lunch” (as a PM&R resident in New York City) to learn about the value of donepezil (Aricept) for the treatment of dementia. I was astonished by the drug’s lack of efficacy – the graph displayed in the PowerPoint show demonstrated a 2-point improvement on the Mini Mental State Exam (MMSE), an effect that...

/ January 21, 2010