Results for: autism
Journal Club Debunks Anti-Vaccine Myths
American Family Physician, the journal of the American Academy of Family Physicians, has a feature called AFP Journal Club, where physicians analyze a journal article that either involves a hot topic affecting family physicians or busts a commonly held medical myth. In the September 15, 2010 issue they discussed “Vaccines and autism: a tale of shifting hypotheses,” by Gerber and Offit, published...
What does “anti-vaccine” really mean?
We frequently use terms like "antivaccine," "antivax," and "antivaxxers." Critics think it's a "gotcha" to ask how we define "antivax." It's not. There are gray areas, but not so gray that the word is never appropriate.
Lies, damned lies, and…science-based medicine?
I realize that in the question-and-answer session after my talk at the Lorne Trottier Public Science Symposium a week ago I suggested in response to a man named Leon Maliniak, who monopolized the first part of what was already a too-brief Q&A session by expounding on the supposed genius of Royal Rife, that I would be doing a post about the Rife...
Pat Schroeder’s endorsement of Rage Reduction Therapy: The Cult of the Celebrity Strikes Again
We all know that misguided celebrities, such as Jenny McCarthy, Oprah, Prince Charles, and Arianna Huffington, pose considerable public health threats. Few know that arguably the most vile form of quackery has been getting the thumbs up from a celebrity hailing from the most rarified heights of power and influence — Representative Patricia Schroeder (D-CO, 1973-1997). The practice I’m referring to is...
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October 8, 2010
The Guatemala syphilis experiment and medical ethics in science-based medicine
Several of the bloggers here at SBM have repeatedly criticized various clinical trials for so-called “complementary and alternative medicine” interventions for various conditions and diseases (or should I say dis-eases?) for being completely unethical. Examples include the misbegotten clinical trial for the Gonzalez protocol for pancreatic cancer, which — surprise, surprise! — ended up showing that patients undergoing Dr. Gonzalez’s combination of...
Chelation: Compounding Pharmacy’s Problems
Chelation is the provision of a substance to increase the body’s excretion of heavy metals. In poisoning situations (lead, aluminum, iron, etc.), chelation is medically necessary, objectively effective, and approved for use. But the same term has a completely different meaning in the alternative medicine universe, where proponents often believe heavy metal toxicity is the “one true cause” of disease, and chelation...
When (Anti-Vax) Politics Intrudes
Over the last decade there has been a needed discussion about the relationship between politics and science. This has mostly been spawned by the perceived “Republican War on Science,” at the center of which is the global warming debate. In reality, both ends of the political spectrum (as evidenced, for example, by the Huffington Post) tend to trump science with ideology. That...
Clinical equipoise versus scientific rigor in cancer clinical trials
A critical aspect of both evidence-based medicine (EBM) and science-based medicine (SBM) is the randomized clinical trial. Ideally, particularly for conditions with a large subjective component in symptomatology, the trial should be randomized, double-blind, and placebo-controlled. As Kimball Atwood pointed out just last week, in EBM, scientific prior probability tends to be discounted while in SBM it is not, particularly for therapies...
Using attacks on science by the anti-vaccine movement as a “teachable moment”
A new study on the connection between vaccines and autism demonstrates two things: there is no connection, and those who think there is are not interested in science unless it supports what they already believe.