Category: Science and Medicine

The Syndrome Syndrome

Have you ever heard of heavy leg syndrome? I hadn’t, until I read this BBC article about it – the British are apparently amused at this peculiarly French medical malady. Heavy leg syndrome is a common diagnosis in France, which alone consumes one third of the world’s drugs for this diagnosis. Diseases certainly vary from population to population based upon genetics, environment,...

/ December 17, 2008

How SHOULD We Discuss Quackery with Innocents and the Not-so-Innocent?

Recents posts by Drs. Albietz and Gorski have highlighted questions that are recurrent on SBM. We are convinced that medicine should be based on real knowledge, to the extent that it exists, and that physicians should be honest; these are matters of science and ethics. How do we reconcile that with heartfelt, if misguided beliefs of patients, their families, and others? When Dr. Albietz...

/ December 12, 2008

Now there’s something you don’t see on TV every day…

I rather like Late Night with Conan O’Brien. Unfortunately, I seldom get to watch, mainly because I usually show up at work sometime between 7:00 and 7:30 AM, and I don’t like watching more than a few minutes of video on my computer. However, Hugh Laurie, star of House, was interviewed by Conan and revealed himself to be not unlike me in...

/ December 11, 2008

Credulous medical reporting

Science and medicine reporting is hard. In this space and otherswe’ve dealt with some of the problems that arise when “generalist” reporters try to “do” science and medicine. And now, CNN has shut down its science unit. Given the increasing complexity of medical and scientific knowledge, this is very bad news. As a fine example of poor medical reporting, let’s look at...

/ December 10, 2008

Direct-To-Consumer Science

Dr. Olivier Ameisen is a prominent French cardiologist who believes that the muscle-relaxant drug baclofen relieves the cravings of alcoholism. This is indeed an interesting, and as yet unsettled, scientific medical question. Dr. Ameisen has decided to take his personal scientific opinion directly to the public in his book – Le Dernier Verre (The Last Glass). The result has been a surge...

/ December 10, 2008

H. influenzae—it ain’t the flu, but it’s still pretty cool

I’ve been thinking about an interesting organism lately, an organism that illustrates some basic principles in science-based medicine. The organism is called Haemophilus influenzae (H flu), a gram-negative bacterium discovered in the late 19th century. H flu has a great story, both in historic and modern times. The brilliant microbiologist Richard Pfeiffer isolated H flu from influenza patients in the late 1800’s...

/ December 8, 2008

Google Trends and the Interest in Alternative Medicine

USA Today has come out with a new survey – apparently, three out of every four people make up 75% of the population. –David Letterman How popular is alternative medicine? One way is to survey people and ask them. Like all surveys, the nature of the question determines the answer. The first, and probably most referenced, and misquoted, article on ‘alternative’ medicine...

/ December 6, 2008

Psychological support and breast cancer – again

Does the degree of efficacy is depend on the time at which it is measured? Apparently so. The case of psychological support and breast cancer longevity again. After an original 1989 report of positive effects on metastatic breast cancer, by 2006- 7 the majority of RCTs on such effects had settled the issue in the negative. This was only after 20 years...

/ December 4, 2008

Open-Access Peer Review: Increasing the Noise To Signal Ratio

Readers of Science Based Medicine are quite familiar with the distressingly common logical leap made by disgruntled healthcare consumers into alternative medicine. It goes something like this: I had a terrible experience with a doctor who [ignored/patronized/misdiagnosed] me and I also heard something horrible in the media about a pharmaceutical company’s misbehavior [hiding negative results/overstating efficacy/overcharging for medications], therefore alternative treatments [homeopathy/acupuncture/energy...

/ December 4, 2008

The science of purging, or the purging of science?

It’s Thanksgiving in the U.S., one of my favorite holidays.  Thanksgiving habits get set down early in life, and the while I may find your lima bean casserole execrable, to you it’s just not Thanksgiving without it. And speaking of excrement, you can expect to see adds encouraging you to “detox” from all of your holiday excesses.  Outside the field of substance...

/ November 27, 2008