Results for: clinical trials

For-profit stem cell clinics, universities, and “pay-to-play” clinical trials for autism

Stem cell therapies show great promise, but as yet the vast majority of that promise has not been validated in rigorous clinical trials. Unfortunately, for-profit stem cell clinics are running clinical trials that require patients to pay to be part of it. These trials are not rigorous. Even more unfortunately, it appears that some universities are also running "pay-to-play" clinical trials that...

/ July 29, 2019

Cell phones and cancer: random chance in clinical trials

The full results of the National Toxicology Program's study of cell phones and cancer are finally in. They are somewhat complicated, but ultimately do not support the idea that cell phones can cause cancer.

/ April 1, 2018

Reporting results from clinical trials is vital for science-based medicine

Clinical trials must report on their outcomes, irrespective their results. Doctors and their patients need all the information, not just the good news stories, to make informed decisions.

/ February 28, 2016

WHO Statement on Reporting Clinical Trials

The World Health Organization (WHO) has recently released a new position statement on mandatory reporting of all interventional clinical trials. This is a positive step in the trend towards higher quality and greater transparency in clinical trials. The underlying ethical concept here is that the public has a right to data that results from experimentation on humans. The researchers do not ethically...

/ April 15, 2015

Clinical trials of homeopathy versus “respect for science”

A few months ago, Steve Novella and I published an article in Trends in Molecular Medicine entitled “Clinical trials of integrative medicine: testing whether magic works?” It was our first foray together into publishing commentary about science-based medicine versus evidence-based medicine, using a topic that we’ve both written extensively about over the years on this blog and our respective personal blogs. Specifically,...

/ March 9, 2015

Do doctors pay attention to negative randomized clinical trials?

We at the Science-Based Medicine blog believe that all medicine, regardless of where it comes from, should be held to a single science-based standard with regards to efficacy, effectiveness, and safety. We tend to focus primarily on “complementary and alternative medicine” (CAM), now more commonly known as “integrative medicine,” because (1) we believe it to be undermining the scientific basis of medicine...

/ September 22, 2014

Clinical trials of integrative medicine: testing whether magic works?

  I just thought that I’d take the editor’s (and, speaking for Steve, the founder’s) prerogative to promote our own efforts. Regular readers of SBM are familiar with our message with respect to randomized clinical trials of highly implausible “complementary and alternative medicine” treatments, such as homeopathy or reiki. Well, believe it or not, Steve and I managed to get a commentary...

/ August 21, 2014

The Center for Inquiry weighs in on the FDA’s mishandling of Stanislaw Burzynski’s clinical trials

The Center for Inquiry points out how what Stanislaw Burzynski is doing corrupts the clinical trial process and harms patients.

/ July 3, 2014

The Science of Clinical Trials

Science-based medicine is partly an exercise in detailed navel gazing – we are examining the use of science in the practice of medicine. As we use scientific evidence to determine which treatments work, we also have to examine the relationship between science and practice, and the strengths and weaknesses of the current methods for funding, conducting, reviewing, publishing, and implementing scientific research...

/ August 28, 2013

Do clinical trials work? It depends on what you mean by “work”

Introduction (Skip to the next section if you want to miss the self-referential blather about TAM.) As I write this, I’m winging my way home from TAM, crammed uncomfortably—very uncomfortably—in a window seat in steerage—I mean, coach). I had been thinking of just rerunning a post and having done with it, sleeping the flight away, to arrive tanned, rested, and ready to...

/ July 15, 2013