Results for: Ioannidis

Critical Thinking in Medicine

Cognitive Errors and Diagnostic Mistakes is a superb new guide to critical thinking in medicine written by Jonathan Howard. It explains how our psychological foibles regularly bias and betray us, leading to diagnostic mistakes. Learning critical thinking skills is essential but difficult. Every known cognitive error is illustrated with memorable patient stories.

/ January 15, 2019

A right to science

Unless forced to do so, the state and federal governments will continue to base law and policy on bad science. Maybe it's time for a constitutional amendment guaranteeing a "right to science."

/ October 11, 2018

Debunking the magical power of the placebo effect for chronic pain (yet again)

The opioid crisis and growing awareness of the dangers of addiction to pain medication are prompting renewed calls for the use of pill placebos in place of active treatments, backed by familiar claims about the magical powers of the placebo.

/ October 10, 2018

Estrogen Matters

Hormone replacement therapy in menopause is safer and more effective than we have been led to believe. A new book examines the evidence and sets the record straight.

/ September 4, 2018

The Debate Is Over: Antidepressants DO Work Better Than Placebo

The idea that antidepressants are no more effective than placebo has been put to rest. They clearly work when used appropriately, although the effect size is not as large as the published studies have suggested.

/ March 6, 2018

Rigor Mortis: What’s Wrong with Medical Science and How to Fix It

Medical research has been plagued by less-than-rigorous practices and a culture that rewards quantity over quality. In a new book, Richard Harris identifies the problems, proposes solutions, and offers hope.

/ January 2, 2018

0.05 or 0.005? P-value Wars Continue

The p-value is under fire yet again, but this time with some quick-and-dirty solutions (and some long-and-onerous ones too) to the problems created by relying on this quick-and-dirty test.

/ August 2, 2017

Can mind-body practices “reprogram” our DNA?

A recent systematic review has been touted as demonstrating that "mind-body" practices like yoga can reprogram our DNA. There are several reasons to doubt these claims, not the least of which is the history of bias in past studies on this topic.

/ June 26, 2017

Responding to SBM Critics

A response to a critic of SBM, and setting the record straight on our actual positions regarding evidence and the practice of medicine.

/ April 19, 2017

Medical science policy in the U.S. under Donald Trump eighty days in

A week after Donald Trump was elected, I speculated about how he would affect medical science policy. Now, 80 days into the Trump administration, we have some observations.

/ April 10, 2017